NCT04931537Recruiting
Screening and Application Research of Early Diabetic Nephropathy Markers Based on Lipidomics.
Source: ClinicalTrials.gov · Last updated 20 Jul 2021 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Diabetic nephropathy (DN) is one of the major microvascular complications associated with diabetic patients, and also the major global cause of chronic kidney disease and end-stage renal disease (ESRD). Albuminuria and estimated glomerular filtration rate (eGFR) are currently recognized clinical indicators for early diagnosis of DN, however, the sensitivity and specificity are unsatisfactory. The early identification and treatment of DKD are conducive to lowering the risk of kidney damage by as much as 50%. Therefore, it is particularly critical to find new biomarkers to reflect the potential DKD lesions in the clinical silent period earlier and more accurately. Therefore, this study intends to analyze the differentially expressed lipids in early DKD, T2DM and healthy adults by mass spectrometry, and verify the related results by larger samples, so as to screen out early markers of DKD and achieve the ultimate goal of clinical application.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1000 (estimated)
- First submitted
- 14 Jun 2021
- Start date
- 1 May 2021
- Primary completion date
- 31 Dec 2023
- Lead sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
- Diseases
- Chronic kidney disease
- NCT number
- NCT04931537
What you commit to
- Study type: Observational
- Planned participants: 1000
- From 1 May 2021 to the primary completion date, 31 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Drug users or drug abusers;
Other illness
- Renal diseases caused by other causes, including primary and secondary;
- All kinds of acute infections;
- The expected life expectancy (life expectancy or related diseases) was less than 5 years according to the researcher's judgment.
- Sexually transmitted diseases such as viral hepatitis, AIDS and syphilis, and infectious diseases such as tuberculosis are in an active period;
Other
- Meet the 1999 World Health Organization (WHO) diagnostic criteria for T1DM、T2DM;
- Any situation judged by the researcher that affects enrollment.
Who the study is looking for
- Subjects who have signed informed consent.
- Subjects were 20-80 years old and of either gender.
- Subjects showed good compliance, and the follow-up data was available for \>5 years.
Age in the registry: 18 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| the Second Affiliated Hospital Zhejiang University Schoolof Medicine Coordinator of this site? Confirm its status | Hangzhou | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.