NCT04936867Completed
The CArdiac Imaging RegistrY Study
The CArdiac Imaging RegistrY Study: Computed ToMogrAphy for Risk Stratification and Diagnostic Safety
Source: ClinicalTrials.gov · Last updated 6 Jan 2026
Brief summary (registry, in English)
In this prospective longitudinal observational investigator-led single centre cohort study we will include patients undergoing cardio-CT for clinical reasons, to evaluate the role of cardio-CT terms of its diagnostic and prognostic value, as well as risk-benefit ratio. Particular aims include: 1. To determine the prevalence of CAD for age, gender, ethnicity relative to established risk models 2. To determine associations between CAD severity and plaque type and: 1. with traditional risk factors (arterial hypertension, diabetes, hypercholesterolemia, smoking) 2. blood markers of increased cardiovascular risk 3. To determine predictive associations of between CAD with outcome (endpoint definitions in appendix) 4. To determine the risk-benefit ratio (number of subsequent interventions, complications, radiation exposure, late onset of cancer diseases, etc).
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 100 (actual)
- First submitted
- 16 Jun 2021
- Start date
- 25 Jul 2017
- Primary completion date
- 1 Jan 2025
- Lead sponsor
- Johann Wolfgang Goethe University Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT04936867
What you commit to
- Study type: Observational
- Participants enrolled: 100
- From 25 Jul 2017 to the primary completion date, 1 Jan 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- known allergy to iodinated contrast agent
- unstable hemodynamic status or arrhythmias
- suspected acute coronary syndrome
Other
- standard contraindications to CT (in line with local roles and guidelines - please see Appendix)
- suspected acute kidney injury
- manifest thyrotoxicosis
Who the study is looking for
- Adults (=/\>18 years of age)
- Able to provide informed consent
- Clinical indication for cardio-CT in line with the latest clinical guidelines
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Institute for experimental and translational cardiovascular imaging Coordinator of this site? Confirm its status | Frankfurt am Main | Germany | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.