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NCT04936867Completed

The CArdiac Imaging RegistrY Study

The CArdiac Imaging RegistrY Study: Computed ToMogrAphy for Risk Stratification and Diagnostic Safety

Source: ClinicalTrials.gov · Last updated 6 Jan 2026

Brief summary (registry, in English)

In this prospective longitudinal observational investigator-led single centre cohort study we will include patients undergoing cardio-CT for clinical reasons, to evaluate the role of cardio-CT terms of its diagnostic and prognostic value, as well as risk-benefit ratio. Particular aims include: 1. To determine the prevalence of CAD for age, gender, ethnicity relative to established risk models 2. To determine associations between CAD severity and plaque type and: 1. with traditional risk factors (arterial hypertension, diabetes, hypercholesterolemia, smoking) 2. blood markers of increased cardiovascular risk 3. To determine predictive associations of between CAD with outcome (endpoint definitions in appendix) 4. To determine the risk-benefit ratio (number of subsequent interventions, complications, radiation exposure, late onset of cancer diseases, etc).

Status (registry)
Completed
Study type
Observational
Enrollment
100 (actual)
First submitted
16 Jun 2021
Start date
25 Jul 2017
Primary completion date
1 Jan 2025
Lead sponsor
Johann Wolfgang Goethe University Hospital
NCT number
NCT04936867

What you commit to

  • Study type: Observational
  • Participants enrolled: 100
  • From 25 Jul 2017 to the primary completion date, 1 Jan 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • known allergy to iodinated contrast agent
  • unstable hemodynamic status or arrhythmias
  • suspected acute coronary syndrome

Other

  • standard contraindications to CT (in line with local roles and guidelines - please see Appendix)
  • suspected acute kidney injury
  • manifest thyrotoxicosis

Who the study is looking for

  • Adults (=/\>18 years of age)
  • Able to provide informed consent
  • Clinical indication for cardio-CT in line with the latest clinical guidelines

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Institute for experimental and translational cardiovascular imaging
Coordinator of this site? Confirm its status
Frankfurt am MainGermanyUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.