NCT04938141Completed
MEOI and HRQoL in CLL Patients Treated With BTKis
Medical Events of Interest and Health-Related Quality of Life in Chronic Lymphocytic Leukemia Patients Initiating Treatment With Bruton's Tyrosine Kinase Inhibitors Acalabrutinib or Ibrutinib
Source: ClinicalTrials.gov · Last updated 22 Oct 2026
Brief summary (registry, in English)
This is a multi-site observational study of medical events of interest (MEOI) and health-related quality of life (HRQoL) in chronic lymphocytic leukemia (CLL) patients initiating treatment with the Bruton's tyrosine kinase inhibitors (BTKi) acalabrutinib or ibrutinib in the United States (US)
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 23 (actual)
- First submitted
- 17 Jun 2021
- Start date
- 7 Oct 2021
- Primary completion date
- 26 Sept 2024
- Lead sponsor
- AstraZeneca
- NCT number
- NCT04938141
What you commit to
- Study type: Observational
- Participants enrolled: 23
- From 7 Oct 2021 to the primary completion date, 26 Sept 2024
- 16 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of BTKi any time prior to study enrollment.
- Currently receiving systemic treatment for another malignancy
Other
- Currently enrolled in a clinical trial
Who the study is looking for
- ≥18 years old
- Physician-confirmed diagnosis of CLL or small lymphocytic lymphoma (SLL)
- BTKi naïve patients who initiate acalabrutinib or ibrutinib treatment alone or in combination with an anti-CD20 mAb within 7 days (before or after) study enrollment\*. Both treatment naïve and relapsed/refractory CLL patients will be included.
- Provides informed consent
- Adequate English reading skills
- Able to access and use a computer, tablet, or smartphone to complete PROs
Sex: All · Does not accept healthy volunteers
Sites (16)
Sites in registry order. Pick your city on the disease page to sort them by distance.
This page is information, not medical advice. Discuss any trial with your doctor.