NCT04938596Completed
Airborne Preventive Measures to Reduce New TB Infections in Household Contacts
Strengthening of Airborne Preventive Measures Inside Households of Pulmonary TB Cases as a Tool to Reduce New Infections in Close Contacts. A Pilot, Controlled, Pre-post Study.
Source: ClinicalTrials.gov · Last updated 13 May 2024
Brief summary (registry, in English)
Tuberculosis (TB) is currently one of the top 10 causes of death worldwide and the leading cause of death from a single infectious agent (ranking above HIV/AIDS). The investigators hypothesize that reducing respiratory exposure within the household, during the first weeks of TB treatment initiation of the index case, can reduce new TB infections in close contacts. For this purpose, a pilot, controlled, pre-post study will be set up, to evaluate the feasibility of implementing a bundle of respiratory precautions to all household contacts of new pulmonary TB cases, compared to standard of care, in primary health care in a high TB incidence area in Santiago, Chile.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 432 (actual)
- First submitted
- 12 May 2021
- Start date
- 4 Oct 2021
- Primary completion date
- 30 Mar 2024
- Lead sponsor
- Pontificia Universidad Catolica de Chile
- Diseases
- Tuberculosis
- NCT number
- NCT04938596
What you commit to
- Study type: Interventional
- Participants enrolled: 432
- From 4 Oct 2021 to the primary completion date, 30 Mar 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- household contacts found to have co-prevalent active TB at enrolment
- household contacts planning to leave the house at the time of enrolment
- household contacts of index cases having already initiated TB treatment for \> 48h
- household contacts of index cases that are currently hospitalized
Who the study is looking for
- all household contacts of a new case of pulmonary TB (smear, culture or PCR positive) newly diagnosed at each clinic.
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Pontificia Universidad Catolica de Chile Coordinator of this site? Confirm its status | Santiago | Chile | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.