NCT04949451Recruiting
Time Restricted Feeding, Muscle, and Metabolism
Time Restricted Feeding Intervention for Muscle and Metabolic Health (TRIMM)
Source: ClinicalTrials.gov · Last updated 26 Aug 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Effective nutrition strategies for combatting and/or preventing obesity still need to be identified. This has been the case despite the numerous and different approaches that have been taken. Potential targets for combatting/preventing obesity have been identified, but long-term solutions have not emerged. This study uses time restricted feeding to study the role of dietary protein in obesity prevention and/or treatment. The objectives are to determine the role of skeletal muscle mass as a driver of energy-sensing mechanisms and peripheral signals that regulate appetite and energy intake in overweight and obese adults and to determine the effects of protein timing on muscle mass to regulate appetite and energy intake in overweight and obese adults.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 90 (estimated)
- First submitted
- 16 Jun 2021
- Start date
- 13 Jun 2021
- Primary completion date
- 30 Apr 2025
- Lead sponsor
- University of Arkansas, Fayetteville
- Diseases
- Obesity
- NCT number
- NCT04949451
What you commit to
- Study type: Interventional
- Planned participants: 90
- From 13 Jun 2021 to the primary completion date, 30 Apr 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently taking protein supplements or other nutritional supplements which may interfere with study outcomes
Other illness
- Food allergies
- Pre-existing health conditions related to obesity (e.g. cardiovascular disease, diabetes, hypertension)
- Prescription medications related to heart disease or type 2 diabetes
Other
- Pregnant or breastfeeding
- Dietary restrictions (e.g. vegetarian, vegan, etc.)
- Trying to lose weight in last 3 months
- Fear of needles
- Smoker or vaping
- Consumes \>4 alcoholic beverages per week
Who the study is looking for
- Resides in Northwest Arkansas
- Age 25-50 years
- BMI \> 25
- All ethnicities
- Female and male
Age in the registry: 25 years to 50 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Arkansas Coordinator of this site? Confirm its status | Fayetteville | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.