NCT04956770Completed
Study on Feasibility of Targeted Epidural Spinal Stimulation (TESS) to Improve Mobility in Patients With Parkinson's Disease
STIMO-PARKINSON: Study on Feasibility of Targeted Epidural Spinal Stimulation (TESS) to Improve Mobility in Patients With Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 1 Jun 2026
Brief summary (registry, in English)
The purpose of the STIMO-PARKINSON study is to evaluate the safety and preliminary efficacy of Targeted Epidural Spinal Stimulation (TESS) system to induce modulation in leg muscle recruitment in patients with advanced Parkinson's disease, and its capacity to improve key gait and balance deficits when employed in the context of a rehabilitation process of 3 to 5 months.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 2 (actual)
- First submitted
- 31 May 2021
- Start date
- 14 Jun 2021
- Primary completion date
- 16 Apr 2026
- Lead sponsor
- Jocelyne Bloch
- Diseases
- Parkinson disease
- NCT number
- NCT04956770
What you commit to
- Study type: Interventional
- Participants enrolled: 2
- From 14 Jun 2021 to the primary completion date, 16 Apr 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe or chronic medical disorder pre-existing PD diagnosis affecting rehabilitation
- Active oncological disease requiring heavy treatments and frequent MRI controls
- Having an implanted device that is active (e.g., pacemaker, implantable cardiac defibrillator) whose interference with the investigational system's neurostimulator (Activa RC) is not confirmed safe by the CE-mark of the device, or having an indication that might lead to implantation of such device
- Inability to follow study procedures, e.g. due to language problems, psychological disorders, dementia as considered by the Investigators in accordance with treating physician and treating neurologist
- Hematological disorders with an increased risk of hemorrhagic event during surgical interventions
Other
- Life expectancy of less than 12 months
- Pregnant or breast feeding
- Participation in another interventional study
Who the study is looking for
- Idiopathic Parkinson's disease with III-IV Hoehn-Yahr stage, exhibiting severe gait difficulties and postural instability
- With Medtronic DBS implant and receiving medication for Parkinson's disease
- Aged 18 to 80 years
- Stable medical, physical and psychological condition as considered by the Investigators in accordance with treating physician and treating neurologist.
- Must agree to comply in good faith with all conditions of the study and to attend all required study training and visit
- Must provide and sign the study's Informed Consent prior to any study-related procedures
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHUV Coordinator of this site? Confirm its status | Lausanne | Switzerland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.