NCT04960059Completed
NOTION: iN-home Sampling Of cyTokines in ImmunOtherapy patieNts
Source: ClinicalTrials.gov · Last updated 19 Mar 2026
Brief summary (registry, in English)
This study will explore the ability of patients on first line combination immunotherapy to sample cytokines at home. The data from this study will be used to evaluate the feasibility of in-home testing and the ability to analyse patients cytokine profiles retrospectively to help feed the development of further studies.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 24 (actual)
- First submitted
- 2 Jul 2021
- Start date
- Feb 2022
- Primary completion date
- Jun 2025
- Lead sponsor
- The Christie NHS Foundation Trust
- Diseases
- Kidney cancer, Melanoma, Lung cancer
- NCT number
- NCT04960059
What you commit to
- Study type: Observational
- Participants enrolled: 24
- From Feb 2022 to the primary completion date, Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous immunotherapy (including any CPI either as single agent on in combination, or high dose interleukin-2).
- Patients receiving long term oral anticoagulation deemed by the clinician to be at risk from daily finger pricking.
Other
- Judgement by the investigator that the individual should not participate if they are unlikely to comply with study procedures and requirements.
Who the study is looking for
- Voluntary informed consent.
- Aged at least 18 years.
- Diagnosis of locally advanced or metastatic RCC, Melanoma or NSCLC
- In the opinion of the investigator deemed suitable to receive first-line combination immunotherapy (RCC and MM) or combination immunotherapy and chemotherapy (NSCLC).
- Willingness to comply with scheduled trial procedures.
- Capable of performing own dry blood sampling procedure, or a carer who is willing and able to perform them.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Christie NHS Foundation Trust Coordinator of this site? Confirm its status | Manchester | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.