NCT04964739Completed
Gender/Sex & CUD Remission
Gender and Sex Hormone Influences on Cannabis Use Disorder Remission
Source: ClinicalTrials.gov · Last updated 10 Nov 2025
Brief summary (registry, in English)
Adults (ages 18+) who would like to reduce their cannabis use (N=224) will be enrolled in an 8-week treatment program. All participants will receive counseling (1 goals session with a therapist followed by 7 weekly computerized cognitive-behavioral therapy sessions). Detailed cannabis assessments (biological and self-report) will be conducted throughout treatment and at 1-, 2-, and 3-months post-treatment completion. Daily electronic diaries will be administered via text message to record detailed logs of cannabis use quantity and frequency. Salivary samples will be collected (and video observed) daily throughout treatment to analyze for progesterone.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 224 (actual)
- First submitted
- 11 Jul 2021
- Start date
- 15 Nov 2021
- Primary completion date
- 27 Oct 2025
- Lead sponsor
- Medical University of South Carolina
- NCT number
- NCT04964739
What you commit to
- Study type: Interventional
- Participants enrolled: 224
- From 15 Nov 2021 to the primary completion date, 27 Oct 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Significant or acutely unstable medical or psychiatric problems (i.e., psychosis, mania) that would contraindicate research procedures, interfere with safety, compromise data integrity, or preclude consistent study participation.
- The presence of any substance use disorder requiring a higher level of care.
Other
- Significant risk of homicide or suicide.
- Pregnant, trying to become pregnant, or breastfeeding.
Who the study is looking for
- Willingness to participate in a research study (otherwise, will be referred to appropriate clinical services if seeking clinical care).
- Meet current (within last 30 days) DSM-5 criteria for cannabis use disorder.
- Submit a positive urine cannabinoid test during screening.
- Interested in treatment for cannabis use disorder.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical University of South Carolina Coordinator of this site? Confirm its status | Charleston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.