NCT04970836Recruiting
The Immune Responses After Hepatitis B Revaccination Doses in a Young Cohort
Source: ClinicalTrials.gov · Last updated 21 Oct 2026
Brief summary (registry, in English)
This prospective cohort study aims to provide the evidence-based clinical guide to help decide the revaccination doses of hepatitis B vaccine that the high-risk young adults without hepatitis B seroprotective antibodies (anti-HBs titer\<10 mIU/mL) need to take.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 240 (estimated)
- First submitted
- 6 Jul 2021
- Start date
- 1 Aug 2021
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- National Taiwan University Hospital
- Diseases
- Hepatitis B
- NCT number
- NCT04970836
What you commit to
- Study type: Interventional
- Planned participants: 240
- From 1 Aug 2021 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Those who were previously allergic to hepatitis B vaccine or its components (such as yeast)
Other illness
- Those who have been vaccinated against hepatitis B during childhood and adolescence
- Those who have a positive test for hepatitis B surface antibody or a positive test for hepatitis B surface antigen
Who the study is looking for
- The actual age at the time of admission was higher than 20 years old and birth year after 1987
- Born in Taiwan and had received a full course of hepatitis B vaccines at least three doses at infant period.
- Those who have tested negative for hepatitis B surface antibody and surface antigen at baseline
- Have never been vaccinated against hepatitis B in childhood and adolescence by questionnaire
- Consent to administer 1-2 doses of hepatitis B vaccine according to the assigned group after sharing decision making process
- In good health
Age in the registry: 20 years to 36 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Family Medicine, NTUH Coordinator of this site? Confirm its status | Taipei | Taiwan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.