NCT04979793TerminatedPhase 1
Role of L-citrulline in Prevention of Pregnancy Associated Hypertension
Role of L-citrulline in Prevention of Pregnancy Associated Hypertension in Nulliparous Women
Source: ClinicalTrials.gov · Last updated 30 Sept 2026
Brief summary (registry, in English)
The target population for our study is healthy nulliparous pregnant women (first pregnancy) between the 12-16 week of pregnancy. If a subject is eligible, written consent will be obtained by person to person contact. Eligible participants will be randomized to receive either daily L-citrulline supplementation or placebo.
- Status (registry)
- Terminated
- Phase (registry)
- Phase 1
- Study type
- Interventional
- Enrollment
- 3 (actual)
- First submitted
- 16 Jun 2021
- Start date
- 28 Jul 2021
- Primary completion date
- 12 Dec 2025
- Lead sponsor
- The University of Texas Medical Branch, Galveston
- Diseases
- High blood pressure
- NCT number
- NCT04979793
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known maternal kidney disease
- Known allergies to study interventions
- Preexisting hypertension (chronic hypertension)
- Known gastric ulcer
Other
- Known fetal anomaly or chromosomal abnormality
- Early fetal growth restriction
- Fetal demise or planned termination
- Participation in another study that may influence this study
- Known maternal electrolyte imbalance
- Incarcerated status
- Planned delivery at non-UTMB hospital
- Known lactose intolerance
Who the study is looking for
- Nulliparous (no previous pregnancy greater than 20 weeks)
- Gestational age of pregnancy between 12 and 16 weeks
Age in the registry: 18 years to - · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Texas Medical Branch Coordinator of this site? Confirm its status | Galveston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.