NCT04981795Completed
realMIND: Observational Study on Safety and Effectiveness of Tafasitamab in Combination With Lenalidomide in Patients With Relapsed or Refractory DLBCL
realMIND: A Multicenter, Observational Study to Characterize the Safety and Effectiveness of Tafasitamab in Combination With Lenalidomide in US Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma With a Focus on Racial and Ethnic Minority Patients
Source: ClinicalTrials.gov · Last updated 27 Apr 2026
Brief summary (registry, in English)
The realMIND study is a multicenter, observational study intended to further characterize the safety and effectiveness data of US patients (with a focus on racial and ethnic minority patients) with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL), treated with tafasitamab in combination with lenalidomide.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 102 (actual)
- First submitted
- 19 Jul 2021
- Start date
- 20 Sept 2021
- Primary completion date
- 23 Jan 2026
- Lead sponsor
- Incyte Corporation
- Diseases
- Diffuse large B-cell lymphoma
- NCT number
- NCT04981795
What you commit to
- Study type: Observational
- Participants enrolled: 102
- From 20 Sept 2021 to the primary completion date, 23 Jan 2026
- 26 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Initiated or initiating tafasitamab treatment in the context of an interventional study.
Criteria the registry did not label
- Criteria: Inclusion Criteria:
- Age ≥18 years at the time of diagnosis of R/R DLBCL
- Initiated or initiating tafasitamab treatment
- R/R DLBCL patients who have received at least one (1) prior line of treatment for DLBCL
- Histologically confirmed DLBCL such as:
- DLBCL not otherwise specified (NOS) b) T-cell histiocyte-rich large B-cell lymphoma (THRLBCL) c) Epstein-Barr virus (EBV)-positive DLBCL of the elderly d) Composite lymphoma with a DLBCL component with a subsequent DLBCL relapse, according to Revised European American Lymphoma (REAL)/World Health Organization (WHO) classification e) Patients with evidence of histological transformation to DLBCL from an earlier diagnosis of low-grade lymphoma (i.e., an indolent pathology such as follicular lymphoma \[FL\], marginal zone lymphoma \[MZL\], chronic lymphocytic leukemia \[CLL\]) with a subsequent DLBCL relapse f) High-grade B-cell lymphoma: i) DLBCL with MYC and BCL2 or BCL6 translocation (double-hit) and MYC and BCL2 and BCL6 translocations (triple-hit) ii) High-grade B-cell lymphoma, NOS
- Signed and dated ICF by the patient or the patient's Legally Acceptable Representative (LAR), for patients with prospective data collection, as applicable. For deceased or otherwise unreachable patients, no informed consent will be obtained for data collection in the study, provided that the competent Independent Ethics Committee (IEC)/Institutional Review Board (IRB) has provided favorable opinion and that any other local regulatory requirements on this matter are met
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (26)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| McFarland Clinic, P.C. Coordinator of this site? Confirm its status | Ames | United States | Unknown status |
| University of Michigan Comprehensive Cancer Center Michigan Medicine Coordinator of this site? Confirm its status | Ann Arbor | United States | Unknown status |
| American Oncology Partners of Maryland, PA Coordinator of this site? Confirm its status | Bethesda | United States | Unknown status |
| Alabama Oncology Coordinator of this site? Confirm its status | Birmingham | United States | Unknown status |
| Mercy Medical Center Coordinator of this site? Confirm its status | Canton | United States | Unknown status |
| Levine Cancer Institute Coordinator of this site? Confirm its status | Charlotte | United States | Unknown status |
| Mission Cancer and Blood Coordinator of this site? Confirm its status | Des Moines | United States | Unknown status |
| Henry Ford Health System Coordinator of this site? Confirm its status | Detroit | United States | Unknown status |
| VA Medical Center - Durham Coordinator of this site? Confirm its status | Durham | United States | Unknown status |
| Duke University Coordinator of this site? Confirm its status | Durham | United States | Unknown status |
| Leo Jenkins Cancer Center/ECU School of Medicine Coordinator of this site? Confirm its status | Greenville | United States | Unknown status |
| Westchester Medical Center Coordinator of this site? Confirm its status | Hawthorne | United States | Unknown status |
| University of Texas - MD Anderson Cancer Center Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
| Clearview Cancer Institute Coordinator of this site? Confirm its status | Huntsville | United States | Unknown status |
| Ohio Health Marion Area Physicians Coordinator of this site? Confirm its status | Marion | United States | Unknown status |
| Tri-County Hematology & Oncology Associates, Inc. Coordinator of this site? Confirm its status | Massillon | United States | Unknown status |
| Froedtert & Medical College Clinics Coordinator of this site? Confirm its status | Milwaukee | United States | Unknown status |
| Morristown Medical Center Coordinator of this site? Confirm its status | Morristown | United States | Unknown status |
| Rutgers Cancer Institute of New Jersey Coordinator of this site? Confirm its status | New Brunswick | United States | Unknown status |
| Tulane Cancer Center Coordinator of this site? Confirm its status | New Orleans | United States | Unknown status |
| Integris Cancer Institute of Oklahoma Coordinator of this site? Confirm its status | Oklahoma City | United States | Unknown status |
| University of California Irvine Medical Center Coordinator of this site? Confirm its status | Orange | United States | Unknown status |
| Thomas Jefferson University Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
| UW Medicine Coordinator of this site? Confirm its status | Seattle | United States | Unknown status |
| Lankenau Medical Center Coordinator of this site? Confirm its status | Wynnewood | United States | Unknown status |
| Yakima Valley Memorial Hospital/ North Star Lodge Coordinator of this site? Confirm its status | Yakima | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.