Sign in

NCT04986748Recruiting

Using QPOP to Predict Treatment for Sarcomas and Melanomas

Q-SAM (Using QPOP to Predict Treatment for Sarcomas and Melanomas)

Source: ClinicalTrials.gov · Last updated 1 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

This is a multi-cohort proof of concept study involving patients with sarcomas or melanomas. Patient models, both two- and three-dimensional, will be derived from tumour samples. These will then be used to evaluate drug sensitivities ex vivo. Enrolled patients will undergo resections or biopsies as part of standard-of-care, which will be used to generate patient models. Patients will receive standard-of-care systemic treatment. Patient models will also be subjected up to a 14-drug screening panel. The majority of drugs in the respective drug panels has been shown to have activity in the respective cancers and would be used in the standard-of-care setting by treating physicians.

Status (registry)
Recruiting
Study type
Observational
Enrollment
100 (estimated)
First submitted
27 Jul 2021
Start date
8 Sept 2020
Primary completion date
31 Oct 2028
Lead sponsor
National Cancer Centre, Singapore
Diseases
Melanoma, Sarcoma
NCT number
NCT04986748

What you commit to

  • Study type: Observational
  • Planned participants: 100
  • From 8 Sept 2020 to the primary completion date, 31 Oct 2028
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • There are no specific exclusion criteria if patients meet the inclusion criteria

Who the study is looking for

  • Diagnosis of sarcoma or melanoma
  • At least 1 tumour lesion amenable to fresh biopsy or resection
  • Signed informed consent from patient or legal representative
  • Able to comply with study-related procedures

Age in the registry: 21 years to 99 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
National Cancer Centre Singapore
Coordinator of this site? Confirm its status
SingaporeSingaporeRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.