NCT04991831Recruiting
A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 20 Mar 2026
Brief summary (registry, in English)
The objectives of this study are to collect the long-term safety and effectiveness data of performing thalamotomy for tremor dominant Parkinson's Disease (TDPD) using the Exablate Neuro system.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 28 Jul 2021
- Start date
- 28 Apr 2022
- Primary completion date
- Dec 2027
- Lead sponsor
- InSightec
- Diseases
- Parkinson disease
- NCT number
- NCT04991831
What you commit to
- Study type: Observational
- Planned participants: 50
- From 28 Apr 2022 to the primary completion date, Dec 2027
- 8 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Subject does not agree to participate or is unlikely to participate for the entirety of the study.
Who the study is looking for
- Men and women, age 30 years and older
- Subject undergoing an Exablate procedure for their planned TDPD treatment; per local institution standard of care.
- Subject is willing to cooperate with the Registry requirements including compliance with the regimen and completion of all study visits
- Subject has signed and received a copy of the approved informed consent form
Age in the registry: 30 years to 99 years · Sex: All · Does not accept healthy volunteers
Sites (8)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Dundee Coordinator of this site? Confirm its status | Dundee | United Kingdom | Recruiting |
| Brigham and Women's Hospital Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
| RUSH University Coordinator of this site? Confirm its status | Chicago | United States | Recruiting |
| Cleveland Clinic Foundation Coordinator of this site? Confirm its status | Cleveland | United States | Recruiting |
| Miami Valley Hospital Coordinator of this site? Confirm its status | Fairborn | United States | Recruiting |
| Novant Health Brain & Spine Surgery Coordinator of this site? Confirm its status | Huntsville | United States | Recruiting |
| Miami Neuroscience Institute Baptist Health Coordinator of this site? Confirm its status | Miami | United States | Recruiting |
| Weill Cornell Medicine Coordinator of this site? Confirm its status | New York | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.