NCT04993859Recruiting

Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children

Source: ClinicalTrials.gov · Last updated 9 Sept 2026

Brief summary (registry, in English)

The over-arching aim of this study is to evaluate the effects of two specific anti-cancer chemotherapies, vincristine and doxorubicin, on bladder function and urine composition.

Status (registry): Recruiting
Study type: Observational
Enrollment: 152 (estimated)
First submitted: 28 Jul 2021
Start date: 2 Jun 2021
Primary completion date: 9 Jul 2031
Lead sponsor: University of Colorado, Denver
Diseases: Childhood cancers
NCT number: NCT04993859

What you commit to

Study type: Observational
Planned participants: 152
From 2 Jun 2021 to the primary completion date, 9 Jul 2031
1 site in 1 country
Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

Pelvic irradiation
Cyclophosphamide or ifosfamide therapy

Other illness

Neurologic disorder

Other

Patients with a:
Primary pelvic tumor
Pre-existing bladder/bowel dysfunction
Spinal defects
Neuro-oncologic tumor or brain metastasis

Who the study is looking for

Children aged 5-13 years old
A history of cancer
Treatment with a chemotherapy regimen including VCR and/or DOX
Completion of chemotherapy at least one year prior to study enrollment and survey completion.

Age in the registry: 5 years to 13 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

Site	City	Country	Site status
Children's Hospital Colorado Coordinator of this site? Confirm its status	Aurora	United States	Recruiting

This page is information, not medical advice. Discuss any trial with your doctor.