NCT04996914Recruiting
Adjuvant Stereotactic Body Radiation Therapy After Trans-arterial Chemoembolization in Hepatocellular Carcinoma
Source: ClinicalTrials.gov · Last updated 11 May 2026
Brief summary (registry, in English)
The study investigates the adjuvant SBRT following TACE in early and intermediate stages HCC not amenable for surgical resection.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 2 Jul 2021
- Start date
- 5 May 2026
- Primary completion date
- 5 May 2028
- Lead sponsor
- RWTH Aachen University
- Diseases
- Liver and biliary tract cancer
- NCT number
- NCT04996914
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 5 May 2026 to the primary completion date, 5 May 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous SIRT
- Previous Sorafenib in the last 8 weeks
Other illness
- Evidence of extrahepatic disease (lymph node or distant metastases)
- History of previous malignancy
Other
- Evidence of macroscopic vascular invasion
- Evidence of an arterio-portal or arterio-venous fistulas
- Pregnant and lactating females
Who the study is looking for
- HCC (diagnosis: histological or radiological)
- Age: 18-80
- Number of lesions 1-3 lesions
- Size of the lesion (or sum of 2-3 lesions) ≥ 4 cm
- Sufficient non-tumorous liver volume (≥ 800 cm3)
- Child Pugh Score: A5-6 or B7-8
- BCLC A or B
- Patient is illegible or refused surgical resection or orthotopic liver transplant
- Blood work (within 2 weeks before registration):
- Absolute neutrophil count (ANC) ≥ 1,500 cells/mm³)
- Platelets ≥50,000 cells/mm³
- AST (and ALT) \< 5 times ULN
- Serum creatinine ≤ ULN or creatinine clearance ≥ 50 mL/min
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| RWTH Aachen University Hospital Coordinator of this site? Confirm its status | Aachen | Germany | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.