NCT05008211Completed
Information-Motivation-Behavioral Skills Model-based Intervention to Domiciliary Non-invasive Ventilation of Patients
Effectiveness of an Information-Motivation-Behavioral Skills Model-based Intervention on Adherence to Domiciliary Non-invasive Ventilation of Patients With Chronic Hypercapnic Respiratory Failure: A Randomized Controlled Study
Source: ClinicalTrials.gov · Last updated 28 Nov 2025
Brief summary (registry, in English)
Domiciliary non-invasive ventilation (NIV) is a standard care for improving survival rates of selected patients with chronic hypercapnic respiratory failure (CHRF) and to improve the patients' hypercapnia, sleep quality, health-related quality of life (QoL). Adherence is an important factor affecting clinical effectiveness of domiciliary NIV. Our previous study has noted the associations between poor domiciliary NIV adherence and increased number of clinical adverse events (p = 0.004) and increased hospitalization requiring acute NIV salvage (p = 0.042). However, there are very limited studies on adherence to domiciliary NIV in patients with CHRF. The only interventional study was a single-group pre-test post-test study and lack of a theoretical framework for guiding the intervention. This study is employing an Information-Motivation-Behavioral skills (IMB) model-based intervention to improve inhalation adherence in a group of chronic obstructive pulmonary disease (COPD) patients.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 124 (actual)
- First submitted
- 9 Aug 2021
- Start date
- 16 Sept 2021
- Primary completion date
- 16 Oct 2024
- Lead sponsor
- The University of Hong Kong
- Diseases
- COPD
- NCT number
- NCT05008211
What you commit to
- Study type: Interventional
- Participants enrolled: 124
- From 16 Sept 2021 to the primary completion date, 16 Oct 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- (1) known psychiatric disorders except anxiety and depression; or
- (2) diseases limiting life expectancy to ≤ one year; or
- (3) active malignancy
Who the study is looking for
- (1) CHRF (i.e., PaCO2 ≥ 7 kPa or 52.5 mmHg) for at least 4 weeks, and
- (2) using domiciliary NIV for ≥ 4 weeks, and
- (3) non-adherer (i.e., used domiciliary NIV for \< 4 hours per night or \< 70% of days or with a mean daily use \< 5 hours per day in the last 2 weeks)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Medicine and Geriatrics, United Christian Hospital Coordinator of this site? Confirm its status | Hong Kong | Hong Kong | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.