NCT05009914Completed
A New Way of Cardiac Denervation to Reduce the Incidence of AF After CABG.
Assessing a New Way of Cardiac Denervation to Reduce the Incidence of Atrial Fibrillation After Coronary Artery Bypass Grafting.
Source: ClinicalTrials.gov · Last updated 13 May 2024
Brief summary (registry, in English)
This is a prospective, random controlled trial(RCT) study. 430 patients undergoing coronary artery bypass grafting were enrolled. Our new way of cardiac denervation, defined as excision of Marshall ligament and Waterstone fat pad, was performed in 215 patients, and the other 215 patients were used as control subjects. All the patients need to equip with electronic monitor to record heart rhythms within 6 days after CABG. The investigators will compare the incidence of postoperative atrial fibrillation between two groups, and follow up 30 days after discharged.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 430 (actual)
- First submitted
- 29 Jun 2021
- Start date
- 15 Aug 2022
- Primary completion date
- 13 Dec 2023
- Lead sponsor
- China National Center for Cardiovascular Diseases
- Diseases
- Atrial fibrillation
- NCT number
- NCT05009914
What you commit to
- Study type: Interventional
- Participants enrolled: 430
- From 15 Aug 2022 to the primary completion date, 13 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Receiving other cardiac surgery except of CABG at the same time, such as Morrow、valvular surgery、ventricular aneurysm surgery、congenital heart diseases surgery；
- Requiring mechanical or pharmacological therapy for hemodynamic support before CABG, such as ECMO or IABP;
Other illness
- Cardiac surgery history；
- History of AF ;
Age
- Age \< 18；
Other
- Emergent CABG;
- Taking antiarrhythmic agents except of beta-blockers last 2 weeks.
Who the study is looking for
- Patients undergoing simple CABG (on-pump/off-pump) for the first time.
- Patients who signed the informed consent form and willing to undergo cardiac denervation.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Coordinator of this site? Confirm its status | Beijing | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.