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NCT05013762Completed

Fast Arm Motor Skill Training in Chronic Stroke Survivors

Fast Training Promotes Recovery of Arm Movements Post-stroke Via Cerebellar-mediated Anticipatory Feedforward Control

Source: ClinicalTrials.gov · Last updated 26 Jun 2026

Brief summary (registry, in English)

Every year, almost 800,000 people experience a stroke in the United States, which lead to upper-limb impairments, making recovery of motor function a priority in stroke rehabilitation. 1) The primary objective of this study is to determine whether fast arm movement training on a tracking task ("Speed-training"), in chronic stroke survivors with mild to moderate paresis, will generalize to improve arm function better than dose-equivalent accuracy training on the same task. 2) study the effect of intensive arm training on the recovery of anticipatory feedforward control. 3) Determine the involvement of cerebellar-cortical circuits in the recovery of arm movements due to speed training.

Status (registry)
Completed
Study type
Interventional
Enrollment
44 (actual)
First submitted
2 Jul 2021
Start date
15 Jun 2021
Primary completion date
1 Sept 2023
Lead sponsor
University of Southern California
Diseases
Stroke
NCT number
NCT05013762

What you commit to

  • Study type: Interventional
  • Participants enrolled: 44
  • From 15 Jun 2021 to the primary completion date, 1 Sept 2023
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • any neurologic diagnoses other than stroke
  • orthopedic disorders affecting the paretic UE
  • severe pain or sensory/proprioceptive impairment in the more affected UE
  • had a stroke directly affecting the cerebellum

Other

  • peripheral movement restrictions, such as neuropathy
  • visual neglect (more than 4% of lines left uncrossed on Albert's test).
  • any contra-indications to MRI scanning
  • mostly resolved impairments with an Upper Extremity Fugl- Meyer motor score \>58/66

Who the study is looking for

  • At least 6 months following an ischemic supratentorial stroke
  • At least 21 years of age
  • Exhibit residual capability to move the paretic UE (Upper Extremity Fugl- Meyer motor score \>20/66)
  • Able to follow a 2-step command (8th item on the MMSE test)
  • Able to perform an unassisted arm reach movement of 25 cm ahead of the body within 5 seconds with trunk restraint
  • Exhibit no greater than mild/moderate spasticity as assessed with a Modified Ashworth Score \< 3

Age in the registry: 21 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Casa Colina Hospital and Centers for Healthcare
Coordinator of this site? Confirm its status
PomonaUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.