NCT05015543Completed
Physical Training in Glioblastoma Patients During Cytotoxic Therapy
Glioblastoma and Sports - Does a Personal Training Program Improve Physical Performance and Quality of Life of Brain Tumor Patients
Source: ClinicalTrials.gov · Last updated 12 Dec 2024
Brief summary (registry, in English)
The aim of the present study is the prospective controlled use of physical activity in a collective of patients with glioblastoma after surgery and concomitant radiation/chemotherapy and during adjuvant cytotoxic therapy. The research question is whether physical exercise is feasible and whether patients benefit physically and mentally from the activities performed. For this purpose, specific training units under the supervision of a certified trainer and sports scientist as well as standardized sports medical test procedures are implemented. Beyond the instructed training, general physical activity phases are recorded electronically using a pedometer/activity tracker, which is worn at all times. It will be examined whether the individual training program 1. improves physical fitness 2. increases quality of life/life satisfaction throughout the intervention 3. can be detected in blood due to increased concentrations of brain-derived neurotrophic factor 1 (BDNF-1) (voluntary) The measurements should be taken before and 8, 16 and 24 weeks after the start of training.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 54 (actual)
- First submitted
- 23 Jun 2021
- Start date
- 23 Jul 2020
- Primary completion date
- 17 Oct 2024
- Lead sponsor
- University Hospital Muenster
- Diseases
- Glioblastoma
- NCT number
- NCT05015543
What you commit to
- Study type: Interventional
- Participants enrolled: 54
- From 23 Jul 2020 to the primary completion date, 17 Oct 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Insufficiently adjusted epilepsy (despite anticonvulsive therapy \> 3 focal seizures per day or \> 1 generalized seizure in the previous 3 days)
Other illness
- Diagnosed dementia (Mini-Mental-State-Test \< 24/30 points)
- Impairment of consciousness
- Acute infection
Other
- Pain (strong, permanent, restricting movement)
- Fever
- Pregnancy and lactation
Who the study is looking for
- Newly diagnosed glioblastoma
- Karnofsky Index ≥ 70
- Eastern Cooperative Oncology Group (ECOG) ≤ 2
- ≥ 18 years
- Completed surgical therapy
- Completed radiation and chemotherapy
- Thrombocytes \> 50.000/µl
- Hb \> 8 mg/dl
- Ability to give consent
- Mother tongue German/very good German skills
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Universitätsklinikum Münster Coordinator of this site? Confirm its status | Münster | Germany | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.