NCT05016531Completed
Optimizing Parameters of Low-Intensity Focused Ultrasound for Cortical Modulation in Stroke Patients
Source: ClinicalTrials.gov · Last updated 7 Aug 2026
Brief summary (registry, in English)
The purpose of this research study is to find out the optimal intensity and frequency of Low Intensity Focused Ultrasound (LIFU) that is safe and tolerable in people who have had a stroke.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 18 (actual)
- First submitted
- 16 Aug 2021
- Start date
- 11 Oct 2021
- Primary completion date
- 17 Apr 2024
- Lead sponsor
- Duke University
- Diseases
- Stroke
- NCT number
- NCT05016531
What you commit to
- Study type: Interventional
- Participants enrolled: 18
- From 11 Oct 2021 to the primary completion date, 17 Apr 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Any concomitant neurological disorder affecting arm function;
Other illness
- Documented history of severe dementia with or without medication before stroke;
- Presence of any MRI/TMS/ultrasonic stimulation risk factors: an electrically, magnetically, or mechanically activated metal or nonmetal implant including cardiac pacemaker, intracerebral vascular clips, or any other electrically sensitive support system; non-fixed metal in any part of the body; pregnancy (the effect of TMS/ultrasonic stimulation on the fetus is unknown); no history of seizure before or after the stroke; preexisting scalp lesion or wound or bone defect or hemicraniectomy.
Other
- Subject is unable to do the motor learning practice at the baseline;
Who the study is looking for
- ≥ 21 years old of any gender and race;
- Clinical ischemic stroke or hemorrhagic (confirmed by CT or MRI) that occurred \>= 2 months ago
- Predominantly unilateral motor impairment with FM-UE score ≤ 62/66;
- MEPs are inducible from a hand muscle on the affected side (i.e. Abductor Pollicis Brevis (APB) muscle).
Age in the registry: 21 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Duke University Hospital Coordinator of this site? Confirm its status | Durham | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.