NCT05024695Active, not recruiting
Evaluate the Safety and Effectiveness of iSTAR Medical's MINIject™ Implant for Lowering Intraocular Pressure (IOP) in Subjects With Primary Open-angle Glaucoma.
A Prospective, Multicenter Masked Clinical Trial to Evaluate the Safety and Effectiveness of the MINIject CS627 Implant in Subjects With Open Angle Glaucoma
Source: ClinicalTrials.gov · Last updated 12 Sept 2025
Brief summary (registry, in English)
Evaluate the safety and effectiveness of iSTAR Medical's MINIject™ implant for lowering intraocular pressure (IOP) in subjects with primary open-angle glaucoma.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 975 (estimated)
- First submitted
- 23 Aug 2021
- Start date
- Aug 2021
- Primary completion date
- Jul 2027
- Lead sponsor
- iSTAR Medical
- Diseases
- Glaucoma
- NCT number
- NCT05024695
What you commit to
- Study type: Interventional
- Planned participants: 975
- From Aug 2021 to the primary completion date, Jul 2027
- 37 sites in 4 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Diagnosed degenerative visual disorders
- Clinically significant intraocular inflammation or infection
Other
- Angle closure, congenital, or secondary glaucoma
Who the study is looking for
- Males and females, 46 years of age or older
- A diagnosis of primary open-angle glaucoma, who are candidates for medical therapy, laser treatment, or glaucoma-filtering surgery
- Pseudophakic with prior uncomplicated cataract surgery
Age in the registry: 46 years to - · Sex: All · Does not accept healthy volunteers
Sites (37)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Institute de l'Oeil des Laurentides Coordinator of this site? Confirm its status | Boisbriand | Canada | Unknown status |
| Clinique Opthalmologies Bellevue Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
| Prism Eye Institute Coordinator of this site? Confirm its status | Oakville | Canada | Unknown status |
| Swiss Glaucoma Research Foundation Swiss Visio Montchoisi Coordinator of this site? Confirm its status | Lausanne | Switzerland | Unknown status |
| Queen Victoria Hospital NHS Foundation Trust Coordinator of this site? Confirm its status | East Grinstead | United Kingdom | Unknown status |
| Imperial College Healthcare NHS Trust Western Eye Hospital Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
| KCL Frost Eye Research Department St Thomas' Hospital Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
| Glaucoma Service Moorfields Eye Hospital Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
| Research & Development Unit, Learning and Research Centre (LaRC), York Hospital Coordinator of this site? Confirm its status | York | United Kingdom | Unknown status |
| LA Eye and Laser Coordinator of this site? Confirm its status | Alexandria | United States | Unknown status |
| Beverly Hills Institute of Ophthalmology Coordinator of this site? Confirm its status | Beverly Hills | United States | Unknown status |
| Minnesota Eye Consultants Coordinator of this site? Confirm its status | Bloomington | United States | Unknown status |
| Reeve Woods Eye Center Coordinator of this site? Confirm its status | Chico | United States | Unknown status |
| Glaucoma Associates of Texas Coordinator of this site? Confirm its status | Dallas | United States | Unknown status |
| Intermountain Eye Center Coordinator of this site? Confirm its status | Eagle | United States | Unknown status |
| El Paso Eye Surgeons Coordinator of this site? Confirm its status | El Paso | United States | Unknown status |
| Vold Vision Coordinator of this site? Confirm its status | Fayetteville | United States | Unknown status |
| Eye Associates of Fort Myers Coordinator of this site? Confirm its status | Fort Myers | United States | Unknown status |
| Ophthalmology Associates Coordinator of this site? Confirm its status | Fort Worth | United States | Unknown status |
| Arizona Advanced Eye Research Institute Coordinator of this site? Confirm its status | Glendale | United States | Unknown status |
| Grand Junction Eye Care Coordinator of this site? Confirm its status | Grand Junction | United States | Unknown status |
| Houston Eye Associates Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
| Berkeley Eye Center Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
| Eye Centers of Racine and Kenosha Coordinator of this site? Confirm its status | Kenosha | United States | Unknown status |
| Center for Sight Las Vegas Coordinator of this site? Confirm its status | Las Vegas | United States | Unknown status |
| Apex Eye Clinical Research, LLC Coordinator of this site? Confirm its status | Mason | United States | Unknown status |
| Vanderbilt Eye Institute Coordinator of this site? Confirm its status | Nashville | United States | Unknown status |
| NYU Langone Ophthalmology Coordinator of this site? Confirm its status | New York | United States | Unknown status |
| Oklahoma Eye Surgeons Coordinator of this site? Confirm its status | Oklahoma City | United States | Unknown status |
| Eye Consultants PC Coordinator of this site? Confirm its status | Omaha | United States | Unknown status |
| Stiles Eyecare Excellene and Glaucoma Institute Coordinator of this site? Confirm its status | Overland Park | United States | Unknown status |
| Illinois Eye Center Coordinator of this site? Confirm its status | Peoria | United States | Unknown status |
| Virdi Eye Clinic Coordinator of this site? Confirm its status | Rock Island | United States | Unknown status |
| Sacramento Eye Consultants, A Medical Corporation Coordinator of this site? Confirm its status | Sacramento | United States | Unknown status |
| The Eye Institute of Utah Coordinator of this site? Confirm its status | Salt Lake City | United States | Unknown status |
| R and R Eye Research Coordinator of this site? Confirm its status | San Antonio | United States | Unknown status |
| Spokane Eye Clinical Research Coordinator of this site? Confirm its status | Spokane | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.