NCT05025774Recruiting
Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise
Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant Bronchopulmonary Dysplasia (BPD, Also Known as Chronic Lung Disease of Prematurity) Through Exercise (FLASHLITE)
Source: ClinicalTrials.gov · Last updated 24 Nov 2025
Brief summary (registry, in English)
This study aims to more accurately assess cardiac function, ventilation and exercise capacity in a non-invasive fashion, and to better characterize exercise intolerance in the setting of three populations of individuals with chronic diseases of childhood (acute lymphoblastic leukemia (ALL), chronic lung disease (CLD) of prematurity, and post-heart transplant (HT))
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 90 (estimated)
- First submitted
- 5 Aug 2021
- Start date
- 14 Mar 2025
- Primary completion date
- 1 Nov 2026
- Lead sponsor
- Masonic Cancer Center, University of Minnesota
- Diseases
- Acute lymphoblastic leukaemia, COPD, Chronic lymphocytic leukaemia, Lung cancer, Childhood cancers
- NCT number
- NCT05025774
What you commit to
- Study type: Observational
- Planned participants: 90
- From 14 Mar 2025 to the primary completion date, 1 Nov 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Cases:
- ALL specific: received cranial radiation, bone marrow transplant recipients
- Investigator or patient's primary physician deems the patient unsuitable for the study
Other illness
- Controls:
- History of malignancy, CLD or HT or any other diagnosis which may reduce cardiorespiratory function
- Investigator deems the patient unsuitable for the study
Who the study is looking for
- Cases:
- Acute lymphoblastic leukemia survivor, OR living with chronic lung disease of prematurity, OR living with heart transplant
- 8-25 years old
- Height: ≥ 48 inches
- Ambulatory without assistance
- English speaking
- Normotensive (\<95th percentile for age; okay if managed with antihypertensive medication)
- SpO2 \>92%
- Not pregnant
- ALL survivor specific: must have completed therapy ≥ 3 months prior to study entry
- Controls
- 8-25 years old
- Height: ≥ 48 inches
- Ambulatory without assistance
- English speaking
- No history of arrhythmia or known cardiac dysfunction at baseline
- Normotensive (\<95th percentile for age; okay if managed with antihypertensive medication)
- SpO2 \>95%
- Not pregnant
Age in the registry: 8 years to 25 years · Sex: All
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Masonic Cancer Center Coordinator of this site? Confirm its status | Minneapolis | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.