NCT05035823Active, not recruiting
COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis
Motor NeuroProsthesis to Restore Motor Control for the COMMAND of Digital Devices: An Early Feasibility Study (EFS) of Safety in Subjects With Severe Quadriparesis
Source: ClinicalTrials.gov · Last updated 8 Sept 2026
Brief summary (registry, in English)
The Synchron motor neuroprosthesis (MNP) is intended to be used in subjects with severe motor impairment, unresponsive to medical or rehabilitative therapy and a persistent functioning motor cortex. The purpose of this research is to evaluate safety and feasibility. The MNP is a type of implantable brain computer interface which bypasses dysfunctional motor neurons. The device is designed to restore the transmission of neural signal from the cerebral cortex utilized for neuromuscular control of digital devices, resulting in a successful execution of non-mechanical digital commands.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 6 (actual)
- First submitted
- 1 Sept 2021
- Start date
- 27 Apr 2022
- Primary completion date
- 19 Sept 2024
- Lead sponsor
- Synchron Medical, Inc.
- NCT number
- NCT05035823
What you commit to
- Study type: Interventional
- Participants enrolled: 6
- From 27 Apr 2022 to the primary completion date, 19 Sept 2024
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Active condition resulting in immunosuppression
- Anaphylactic allergy to contrast media
- Allergy to nickel
- History of pulmonary embolism
- History of recent deep vein thrombosis
- Psychiatric or psychological disorder
- Unable to provide evidence of COVID vaccination
Other
- Unsuitable for general anesthesia
- No study partner or caregiver
Who the study is looking for
- Severe quadriparesis
- Able to give consent
- Appropriate candidate for neurointerventional procedure
- Able and willing to access all clinical testing and not impeded by geographical location
- Proficient in English
- Have a study partner
Age in the registry: 21 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University at Buffalo Neurosurgery (UBNS) Coordinator of this site? Confirm its status | Buffalo | United States | Unknown status |
| Mount Sinai Health System Coordinator of this site? Confirm its status | New York | United States | Unknown status |
| University of Pittsburgh Medical Center Coordinator of this site? Confirm its status | Pittsburgh | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.