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NCT05036486Active, not recruiting

The Registry of Genetic Alterations of Taiwan Biliary Tract Cancer

Source: ClinicalTrials.gov · Last updated 2 Jul 2026

Brief summary (registry, in English)

Recent progress in comprehensive genomic profiling for advanced BTC has helped to clarify tumorigenesis and facilitate the coming era of precision medicine. To further elucidate the underlying molecular genomic aberrations, as well as the clinical demographics and therapeutic outcomes, it is necessary to have a national, multi-centers and population-focused research project to collect data completely. Tumor tissue will be collected from advanced BTC patients for real-time next-generation sequencing analysis in a platform of data storage and sharing. The purpose of the precision medicine project is to establish tumor molecular profiling of BTC populations in Taiwan, to facilitate patients to have corresponding potential targeted therapeutics and suitable clinical trials.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
480 (actual)
First submitted
9 Aug 2021
Start date
Oct 2021
Primary completion date
Dec 2030
Lead sponsor
National Health Research Institutes, Taiwan
NCT number
NCT05036486

What you commit to

  • Study type: Observational
  • Participants enrolled: 480
  • From Oct 2021 to the primary completion date, Dec 2030
  • 13 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Other malignancy within the past 1 years except adequately treated basal or squamous cell skin cancer or cervical cancer in situ.

Other

  • Inability to cooperate by providing a complete medical history.
  • No available tumor tissues for genetic testing.
  • Undesirable compliance.

Who the study is looking for

  • Ages 20 and above.
  • Pathological reported showed adenocarcinoma or adenosquamous carcinoma for patients with BTC (include IHCC, EHCC, GBC or AVC) or hepatocholangiocarcinoma as locally advanced or metastatic status.
  • Willingness to provide the residual biopsy/operative slides.
  • Life expectancy more than 3 months.
  • Patients fully understand the protocol with the willingness to have regular follow-up.
  • Patients are ready to have 1st systemic treatment or under 1st line therapy
  • Total bilirubin ≦5 mg/dL, and ECOG≦2

Age in the registry: 20 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (13)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Chang-Gung Memorial Hospital - Chiayi
Coordinator of this site? Confirm its status
Chiayi CityTaiwanUnknown status
Kaohsiung Chang Gung Memorial Hospital
Coordinator of this site? Confirm its status
Kaohsiung CityTaiwanUnknown status
Kaohsiung Medical University Chung-Ho Memorial Hospital
Coordinator of this site? Confirm its status
Kaohsiung CityTaiwanUnknown status
China Medical University Hospital
Coordinator of this site? Confirm its status
TaichungTaiwanUnknown status
National Cheng Kung University Hospital
Coordinator of this site? Confirm its status
TainanTaiwanUnknown status
MacKay Memorial Hospital
Coordinator of this site? Confirm its status
TaipeiTaiwanUnknown status
Taipei Medical University-Shuang Ho Hospital
Coordinator of this site? Confirm its status
TaipeiTaiwanUnknown status
Tri-Service General Hospital
Coordinator of this site? Confirm its status
TaipeiTaiwanUnknown status
National Taiwan University Hospital
Coordinator of this site? Confirm its status
TaipeiTaiwanUnknown status
Taipei Veterans General Hospital
Coordinator of this site? Confirm its status
TaipeiTaiwanUnknown status
Koo Foundation Sun Yat-Sen Cancer Center
Coordinator of this site? Confirm its status
TaipeiTaiwanUnknown status
Linko Chang Gung Memorial Hospital
Coordinator of this site? Confirm its status
TaoyuanTaiwanUnknown status
Taoyuan General Hospital, Ministry of Health and Welfare
Coordinator of this site? Confirm its status
TaoyuanTaiwanUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.