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NCT05039788Completed

Observational Single-center Study of the Relationship Between Arterial Hypertension and Hypervolemia Defined by Self-measurement of Impedancemetry in Kidney Transplant Patients With Transplantation Less Than 6 Months Old

Monocentric Observational Study to Determine the Relationship Between Arterial Hypertension and Hypervolaemia, Defined by Self-measurement of Impedancemetry in Kidney Transplant Recipients Under 6 Months Old

Source: ClinicalTrials.gov · Last updated 13 May 2026

Brief summary (registry, in English)

The working hypothesis is that hypertension during the first post-transplant trimester is partly explained by the patient's hypervolemia. The main objective of the single-center observational study "HTA ô Connect" is to study the relationship between hypertension and extracellular hyperhydration, thanks to repeated self-measurements of blood pressure and impedancemetry between the 30th and the 90th day post-transplant, in 150 incident kidney transplant patients from our department, the ITUN (Institute of Urology-Nephrology Transplantation). The study population involves 150 incident kidney transplant patients, presenting to the Nantes University Hospital Transplant Institute for 1 month (D30), and presenting with hypertension ≥ 140/90mmHg and not treated with a diuretic. Data collected at the patients' homes will be used to establish a relationship between blood pressure and extracellular water volume. The data collected will not be used to follow up patients who participated in the study in this first stage of exploration.

Status (registry)
Completed
Study type
Observational
Enrollment
57 (actual)
First submitted
8 Jun 2021
Start date
14 Oct 2021
Primary completion date
17 Mar 2026
Lead sponsor
Nantes University Hospital
NCT number
NCT05039788

What you commit to

  • Study type: Observational
  • Participants enrolled: 57
  • From 14 Oct 2021 to the primary completion date, 17 Mar 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Patients treated with diuretics on the day of inclusion

Other illness

  • History of non-renal transplantation

Other

  • Minors, adults under guardianship and protected persons

Who the study is looking for

  • Age ≥ 18 years
  • Blood pressure ≥ 140/90mmHg on 3 occasions and according to the recommendations of the French Society of Hypertension (6) at the M1 consultation
  • Patients 1 to 6 months post-kidney transplant
  • Isolated kidney transplant patient
  • BMI between 16 and 34 kg/cm2
  • Not opposed to the research

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Nantes University Hospital
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NantesFranceUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.