NCT05046535Completed
The Effect of Cigarette Smoke on Sleep Quality and Physical Activity in People With Multiple Sclerosis
Source: ClinicalTrials.gov · Last updated 14 Jun 2024
Brief summary (registry, in English)
Current evidence suggests that cigarette smoke increases disease progression in people with multiple sclerosis (PwMS) and worsen their symptoms. 70% of PwMS report sleep disturbances that negatively affects their quality of life. Cigarette smoke has been found to be associated with sleep disturbances in healthy adult smokers, but this relationship is unknown in PwMS. Also, those who smoke cigarettes have less physical endurance resulting in undesirable effects on physical activity. Also, current evidence suggests that genes play a major role in smoking behavior and that certain genetic differences greatly affects nicotine dependence. To our knowledge, this was never explored before among PwMS. This study aims to explore the association between cigarette smoke, sleep quality, and physical activity in PwMS. Another aim is to explore the genetic susceptibility of people with MS to cigarette smoke, specifically to nicotine dependence
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 72 (actual)
- First submitted
- 5 Sept 2021
- Start date
- 1 Sept 2021
- Primary completion date
- 1 Feb 2024
- Lead sponsor
- University of Jordan
- Diseases
- Multiple sclerosis
- NCT number
- NCT05046535
What you commit to
- Study type: Observational
- Participants enrolled: 72
- From 1 Sept 2021 to the primary completion date, 1 Feb 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Acute ischemic cardiovascular event or coronary artery bypass surgery less than 3 months ago
- Uncontrolled blood pressure with medication (BP\>190/110mmHg).
Other illness
- A neurological disease other than MS
- Orthopedic problems or other conditions that may significantly interfere with testing
Other
- Uncorrected vision loss
Who the study is looking for
- Confirmed diagnosis of MS from a neurologist using the McDonald diagnostic criteria
- Ability to ambulate independently with or without an assistive device
- Current, previous, and nonsmokers
- Age ≥ 18 years
- Ability to give informed consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cell Therapy Center Coordinator of this site? Confirm its status | Amman | Jordan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.