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NCT05053932Completed

Long-term Comparative Cerebrovascular Outcome After Transplantation vs Standard Care in Sickle Cell Anemia

Long-term Comparative Cerebrovascular Outcome After Transplantation vs Standard Care in Children With Sickle Cell Anemia ( DREPAGREFFE-2)

Source: ClinicalTrials.gov · Last updated 15 Jun 2026

Brief summary (registry, in English)

The purpose of the present observational study is to remotely reevaluate the cohort of 67 sickle cell patients with transcranial Doppler-detected cerebral vasculopathy included in the national "Sickle Cell Transplant" protocol and whose 1- and 3-year results were published in JAMA (Journal of the American Medical Association) in 2019 and in BHJ in 2020.

Status (registry)
Completed
Study type
Observational
Enrollment
67 (actual)
First submitted
12 May 2021
Start date
7 Oct 2022
Primary completion date
5 Jan 2025
Lead sponsor
Centre Hospitalier Intercommunal Creteil
NCT number
NCT05053932

What you commit to

  • Study type: Observational
  • Participants enrolled: 67
  • From 7 Oct 2022 to the primary completion date, 5 Jan 2025
  • 14 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Refusal to participate
  • Patient deceased

Who the study is looking for

  • Patient of legal age or minor who participated in the DREPAGREFFE research protocol \[NCT 01340404\] between December 2010 and June 2013,
  • Having read and understood the information letter

Age in the registry: 13 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (14)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Groupe Hospitalier Pellegrin
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BordeauxFranceUnknown status
Hôpital Henri Monr - APHP
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CréteilFranceUnknown status
Centre Hospitalier Intercommunal de Créteil
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CréteilFranceUnknown status
CHU de la Guadeloupe
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La GuadeloupeFranceUnknown status
Hôpital Bicêtre AP-HP
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Le Kremlin-BicêtreFranceUnknown status
IHOPe
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LyonFranceUnknown status
CHU de Lyon
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LyonFranceUnknown status
Hopital de la Timone
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MarseilleFranceUnknown status
CHU de Montpellier
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MontpellierFranceUnknown status
Hôpital Robert-Debré Ap-Hp
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ParisFranceUnknown status
Hôpital Necker AP-HP
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ParisFranceUnknown status
CH de Pau
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PauFranceUnknown status
CHU de Rennes
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RennesFranceUnknown status
Hopital Hautepierre
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StrasbourgFranceUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.