NCT05058846Terminated
Pilot Study of Pancreatic Cancer Screening
Source: ClinicalTrials.gov · Last updated 26 Oct 2026
Reason given: Slow accrual
Brief summary (registry, in English)
This study investigates how often abnormal findings from routine magnetic resonance imaging occur in people with genetic mutations in BReast CAncer gene. (BRCA), ataxia telangiectasia mutated gene (ATM), or PALB2 screened for pancreatic cancer. This study may lead to a greater understanding of cancer and potentially, improvements in cancer screening and treatment.
- Status (registry)
- Terminated
- Study type
- Observational
- Enrollment
- 64 (actual)
- First submitted
- 17 Sept 2021
- Start date
- 20 Jan 2022
- Primary completion date
- 19 Oct 2026
- Lead sponsor
- University of California, San Francisco
- Diseases
- Pancreatic cancer
- NCT number
- NCT05058846
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior or active pancreatic cancer.
Other
- Pregnant women are excluded from this study because effects of an MRI on developing fetus is unknown.
Who the study is looking for
- Ability to provide consent and willing, and able to comply with study procedures Ability to read and speak English
- GROUP I:
- Documentation of pathogenic or likely pathogenic germline BRCA 1 and 2, ATM or PALB2 germline genetic mutation
- No strong family history of pancreatic cancer (defined as having >= 1 first-degree or second-degree relative with a history of pancreatic cancer)
- Age >= 50 years old at time of consent.
- GROUP II:
- Documentation of pathogenic or likely pathogenic germline BRCA 1 and 2, ATM, or PALB2 germline genetic mutation
- Has strong family history of pancreatic cancer (defined as having >= 1 first-degree or second-degree relative with a history of pancreatic cancer)
- Age >= 18 years old at time of consent (screening generally begins 10 years prior to the earliest pancreatic cancer in the family)
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of California San Francisco | San Francisco | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.