NCT05065840Active, not recruiting
Advancing HPV Vaccination Among HIV Positive Adults: The CHAMPS Study
Implementing an Evidence-Based, Multilevel Intervention to Promote HPV Vaccination Among HIV Positive Adults
Source: ClinicalTrials.gov · Last updated 14 May 2026
Brief summary (registry, in English)
People living with HIV (PLWH) are 28 times more likely to be diagnosed with Human Papillomavirus (HPV) - associated anal cancer than the general population. The HPV vaccine is an effective and safe approach to prevent and reduce the risk of HPV-related disease among PLWH. HPV vaccine programs tailored and implemented in the HIV population are lagging for this high-risk group. The CDC's 4 Pillars Transformation Program is a multi-level, evidence-based intervention that has been successfully used to increase HPV vaccination in the general population and is ready to be tested in the high-risk HIV population, particularly PLWH in the rural South. This program offers providers and clinic staff evidence-based strategies to increase HPV vaccination uptake via training and educational resources. This study proposes to tailor and refine the 4 Pillars Program and conduct this project in three HIV clinics in Georgia.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 267 (actual)
- First submitted
- 22 Sept 2021
- Start date
- 22 May 2023
- Primary completion date
- 1 Feb 2028
- Lead sponsor
- Emory University
- Diseases
- HIV
- NCT number
- NCT05065840
What you commit to
- Study type: Interventional
- Participants enrolled: 267
- From 22 May 2023 to the primary completion date, 1 Feb 2028
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Has contraindications to receiving the HPV vaccine i.e., history of an anaphylactic allergy to latex, an immediate hypersensitivity to yeast, current moderate or severe acute illness, and/or are currently pregnant)
Who the study is looking for
- HIV positive
- 18-45 years of age
- Can read and speak English
- Capable of providing informed consent
- Has not previously received three series HPV vaccine
- No contraindications to receiving HPV vaccine (i.e. history of anaphylactic allergy to later, an immediate hypersensitivity to yeast, current moderate or severe acute illness, and/or are currently pregnant).
Age in the registry: 18 years to 45 years · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Albany Rural Model Clinic Coordinator of this site? Confirm its status | Albany | United States | Unknown status |
| AID Atlanta Coordinator of this site? Confirm its status | Atlanta | United States | Unknown status |
| Faebris Coordinator of this site? Confirm its status | Atlanta | United States | Unknown status |
| AHF Lithonia Coordinator of this site? Confirm its status | Lithonia | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.