NCT05068934Completed
The Relationship Between Epicardial Fat Tissue and Cardiac Function in HFpEF Patients
The Relationship Between Epicardial Fat Tissue and Cardiac Function in HFpEF
Source: ClinicalTrials.gov · Last updated 6 Jan 2026
Brief summary (registry, in English)
Heart failure with preserved ejection fraction (HFpEF) refers to a group of symptoms and signs of heart failure, normal or near-normal left ventricular systolic function (EF\>50%), and ventricular muscle diastolic dysfunction and A clinical syndrome characterized by decreased compliance and increased stiffness. The pathogenesis of HFpEF is related to impaired lipid metabolism and inflammation. Epicardial adipose tissue (Epicardial Adipose tissue, EAT) is a kind of visceral adipose tissue. Related studies have shown that extracardiac Membrane fat is related to inflammation markers, cardiometabolic risk and cardiovascular disease.However, there is still no research investigating the the relationship between epicardial fat thickness and Cardiac Function in HFpEF patients.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 1083 (actual)
- First submitted
- 26 Sept 2021
- Start date
- 12 Oct 2020
- Primary completion date
- 10 Dec 2025
- Lead sponsor
- Dongying Zhang
- Diseases
- Heart failure
- NCT number
- NCT05068934
What you commit to
- Study type: Observational
- Participants enrolled: 1083
- From 12 Oct 2020 to the primary completion date, 10 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe liver failure;
- Primary pulmonary hypertension;
Lab values
- LVEF less than 45% at any time;
Age
- Age \<18 years old.
Who the study is looking for
- Adult aged \>=18years old;
- Diagnosed with HFpEF.
- Diagnostic criteria including:
- left ventricular ejection fraction ≥50%；
- with the symptoms and/or signs of heart failure；
- BNP≥35 pg/mL and/or NTproBNP≥125 pg/mL；
- at least one additional criterion: relevant structural heart disease(LVH and/or LAE) or diastolic dysfunction
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Affiliated Hospital of Chongqing Medical University Coordinator of this site? Confirm its status | Chongqing | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.