NCT05076747Completed
Exercise and Genotype in Sub-acute Stroke
Promoting Brain Plasticity During Sub-acute Stroke: the Interactive Role of Exercise and Genotype
Source: ClinicalTrials.gov · Last updated 11 Dec 2024
Brief summary (registry, in English)
This study will investigate the impact of cardiovascular exercise on brain plasticity among patients in sub-acute stages after stroke, and whether genotype modulates the response to this intervention. Participants in the experimental group will perform cardiovascular training for 8 weeks, three times/week in addition to standard therapy, while participants in the control group will perform standard therapy only. Assessments will be performed at baseline, four weeks, and 8 weeks after training.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 70 (actual)
- First submitted
- 21 Sept 2021
- Start date
- Jun 2021
- Primary completion date
- Nov 2023
- Lead sponsor
- McGill University
- Diseases
- Stroke
- NCT number
- NCT05076747
What you commit to
- Study type: Interventional
- Participants enrolled: 70
- From Jun 2021 to the primary completion date, Nov 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Major psychiatric or previous neurological disease
Other illness
- Hemorrhagic stroke
- Cognitive impairment/dysphasia affecting informed consent
Other
- Concurrently enrolled in another exercise program
- Absolute contraindications to TMS or exercise
Who the study is looking for
- Individuals 40-80 years old
- Who had a first-ever ischemic (cortical or subcortical) stroke confirmed by MRI/CT
- Who had stroke 2 to 6 weeks prior to participation
- With recordable motor-evoked potentials (MEPs) elicited with transcranial magnetic stimulation (TMS) from the affected hemisphere
- With no serious musculoskeletal or neurological conditions other than stroke
- With sufficient cognitive/communicative capacity to safely perform the protocols.
Age in the registry: 40 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Jewish Rehabiliation Hospital Coordinator of this site? Confirm its status | Laval | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.