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NCT05081713Recruiting

Locomotor Recovery and Compensation Post-stroke (LRC)

Source: ClinicalTrials.gov · Last updated 5 Mar 2026

Brief summary (registry, in English)

The proposed research will characterize of the time course of neurological and locomotor recovery as well as development of compensatory strategies throughout sub-acute and chronic phases post stroke. In addition, we will also investigate the extent to which measures of recovery and compensation are malleable and can be altered with specific interventions in both the early and late stages post-stroke. Delineation of the time course of development and magnitude of patterns of recovery and compensation should result in alternative predictive "rules' regarding how patients early post-stroke could recovery functional and neurological function.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
150 (estimated)
First submitted
24 Sept 2021
Start date
1 Sept 2021
Primary completion date
28 Feb 2028
Lead sponsor
Indiana University
Diseases
Stroke
NCT number
NCT05081713

What you commit to

  • Study type: Interventional
  • Planned participants: 150
  • From 1 Sept 2021 to the primary completion date, 28 Feb 2028
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study design.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • other orthopedic or neurological disorder that limited walking prior to stroke

Other illness

  • uncontrolled cardiovascular, metabolic or respiratory disease that limits exercise participation (e.g., congestive heart failure, resting blood pressure \> 200/110 mmHg, uncontrolled diabetes, end-stage renal disease)

Other

  • absolute criteria for termination of exercise testing during initial and repeated ECG testing during graded exercise testing using ACSM guidelines .

Who the study is looking for

  • individuals early post-stroke (\<15-30 days)
  • first ever stroke
  • unilateral hemiparesis
  • currently receiving inpatient rehabilitation
  • ability to follow 1-step commands
  • provision of informed consent
  • medical clearance from the rehabilitation physician to participate. \\

Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Rehabilitation Hospital of Indiana
Coordinator of this site? Confirm its status
IndianapolisUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.