NCT05090865Completed
Dietary Potassium Liberalization in Pre-Dialysis Patients
Dietary Potassium Liberalization With Fruit and Vegetables Versus Potassium Restriction in People With Chronic Kidney Disease (DK-Lib CKD) Trial
Source: ClinicalTrials.gov · Last updated 17 Sept 2026
Brief summary (registry, in English)
The study will look at the impact of the potassium content in fruits and vegetables, on serum potassium concentrations in people with Chronic Kidney Disease (CKD) using a randomized crossover design. Participants will receive home delivery of fruit and vegetables with either higher or lower potassium content in a random order. Clinical chemistry markers from blood and urine samples, blood pressure, physical functioning and health related quality of life will be assessed throughout the duration of the trial. This study will also measure their physical functioning, using a chair stand test. The results of this study could change the dietary recommendations for people with CKD related to potassium.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 30 (actual)
- First submitted
- 12 Oct 2021
- Start date
- Jan 2024
- Primary completion date
- Aug 2026
- Lead sponsor
- University of Manitoba
- Diseases
- Chronic kidney disease
- NCT number
- NCT05090865
What you commit to
- Study type: Interventional
- Participants enrolled: 30
- From Jan 2024 to the primary completion date, Aug 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- In the opinion of the investigator any medical condition, uncontrolled systemic disease or concurrent illness that would decrease the study compliance or jeopardize the safety of the participant
Other illness
- Chronic obstructive pulmonary disease that requires the participant to be on oxygen
- New York Heart Association Class 3-4 Heart symptoms or heart, liver or renal transplant
- A myocardial infarction or stroke within the last 6 months
Lab values
- Serum potassium concentration \> 5.6 mEq/L, anuria, dialysis, or acute kidney injury failure in the 6 months prior to screening
- Currently on potassium binding therapy
Other
- Unable to consume study treatments or control, such as swallowing or gastro-intestinal issues
- Female participant who is pregnant or lactating
Who the study is looking for
- Male or female, aged 18 years or above
- Participants who have an estimated glomerular filtration rate between 15 and 45 ml/min/1.73m2
- Serum potassium concentration between 4.5 and 5.5 milliequivalent (mEq)/L
- Hemoglobin A1c ≤ 11%
- Systolic and diastolic blood pressure \<160/100 mmHg
- Are registered in the multidisciplinary nephrology clinic in Winnipeg
- Able to communicate in English and provide written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Health Sciences Centre Coordinator of this site? Confirm its status | Winnipeg | Canada | Unknown status |
| Seven Oaks General Hospital Chronic Disease Innovation Centre Coordinator of this site? Confirm its status | Winnipeg | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.