NCT05092672Completed
Physical Activity, Air Pollution, and High Blood Pressure
Impact of Traffic-related Air Pollution on the Cardiovascular and Pulmonary Response to Physical Activity in Patients With Hypertension
Source: ClinicalTrials.gov · Last updated 12 Aug 2024
Brief summary (registry, in English)
The investigators are investigating the effects of traffic-related air pollution (TRAP) on the cardiovascular and pulmonary response to exercise in patients with hypertension using a real world randomized, crossover study design. Participants will be exposed to 2 conditions: a low TRAP environment and a high TRAP environment. Each exposure will consist of 30 min of moderate-intensity exercise. Cardiovascular and pulmonary health outcomes will be measured before, during, and up to 24 hours following exposures. A minimum washout period of 1 week will be used to minimize carryover effects.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 21 (actual)
- First submitted
- 28 Sept 2021
- Start date
- 15 Nov 2021
- Primary completion date
- 1 Aug 2024
- Lead sponsor
- University of British Columbia
- Diseases
- High blood pressure
- NCT number
- NCT05092672
What you commit to
- Study type: Interventional
- Participants enrolled: 21
- From 15 Nov 2021 to the primary completion date, 1 Aug 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Hormone replacement therapy use
- Currently on beta-blocker or angiotensin receptor blocker (ARB) therapy
- Currently using over the counter drugs or supplements that may alter cardiovascular measures (as per the principal investigator's discretion)
- Prior diagnosis of any other existing cardiovascular or pulmonary diseases and/or conditions (other than hypertension)
Other
- Current or ex-smokers (abstinent for less than one year)
- Lives with an individual who currently smokes cigarettes, e-cigarettes (i.e., vaping), or cannabis
- Musculoskeletal injury or lower limb limitation preventing safe engagement in moderate-intensity exercise
Who the study is looking for
- Age between 40-70 years of age
- Previously diagnosed with elevated blood pressure or hypertension by a physician
Age in the registry: 40 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of British Columbia Coordinator of this site? Confirm its status | Vancouver | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.