E-Health for Zero Infections - Facilitating Access to and Use of HIV Pre-Exposure Prophylaxis (PrEP) in the Netherlands

Prior treatment

• Chronic use of medication that interacts with TFV/FTC e.g. NSAIDs.

Other illness

• HIV infection;
• Chronic or acute Hepatitis B virus infection;
• Other medical conditions that require special attention when using PrEP, such as osteoporosis or other bone diseases;

Lab values

• eGFR less than 60 mL/min/1.73m2;

Other

• Diminishing renal function:
• Other renal problems, as diagnosed by a physician and advised against using TFV;
• Unlikely, in the opinion of the clinician, to comply with the study requirements or procedures;
• Participating in another study that affects the primary or secondary outcome measures of our study;
• Investigators or otherwise dependent persons.

• Aged 18 years or older;
• Meeting the eligibility criteria of the NPP i.e. being a MSM or transgender persons who in the 6 months prior to the PrEP-request/PrEP-consultation:
  • Had anal sexual intercourse without a condom with a male partner with an un-known HIV status, and/or;
  • Had anal sexual intercourse without a condom with a male partner with a known HIV-positive status and a detectable viral load, and/or;
  • Was diagnosed with a rectal STI, and/or;
  • Received a prescription for post-exposure prophylaxes (PEP);
• Living in the catchment area of one of the participating GGD regions;
• Having a smartphone, internet access and email address;
• Sufficient understanding of Dutch or English; and
• Signed informed consent.