NCT05093673Recruiting
Cerebellar Stimulation for Aphasia Rehabilitation
Source: ClinicalTrials.gov · Last updated 20 Mar 2026
Brief summary (registry, in English)
The optimal site of neuromodulation for post-stroke aphasia has yet to be established. This study will investigate whether multiple sessions of cerebellar transcranial direct current stimulation (tDCS) boosts language therapy in helping people recover from aphasia as well as predict who is likely to respond to cerebellar tDCS.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 13 Oct 2021
- Start date
- 25 Oct 2021
- Primary completion date
- 1 Sept 2027
- Lead sponsor
- Johns Hopkins University
- Diseases
- Stroke
- NCT number
- NCT05093673
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 25 Oct 2021 to the primary completion date, 1 Sept 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous neurological disorder (other than stroke) affecting the brain, or any other neurodegenerative disorder or psychiatric disorder
- Seizures during the previous 6 months
Other illness
- Use of medications that lower the seizure threshold (e.g., methylphenidate)
- History of brain surgery or any metal in the head
- Individuals with severe claustrophobia, cardiac pacemakers or ferromagnetic implants, and pregnant women will be excluded from the MRI portion of the study.
Other
- Lesion in the right cerebellum
- Uncorrected visual loss or hearing loss by self-report
- Use of N-methyl-D-aspartate (NMDA) antagonists (e.g., memantine)
- Severely impaired auditory comprehension (lower than 2 on the Comprehension subscore on the Western Aphasia Battery-Revised)
- Severely limited verbal output (lower than 2 on the Spontaneous Speech rating scale on the Western Aphasia Battery-Revised)
Who the study is looking for
- Chronic ischemic or hemorrhagic left hemisphere stroke
- Fluent speaker of English by self-report
- Age 18 or older
- 6 months post onset of stroke
- Diagnosis of aphasia and naming impairment using the Western Aphasia Battery-Revised
Age in the registry: 18 years to 99 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Johns Hopkins Hospital Coordinator of this site? Confirm its status | Baltimore | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.