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NCT05099315Recruiting

Microbiome in Atopic Dermatitis Under Systemic Therapy

Identification of Skin-associated Microbiota in Atopic Dermatitis Patients Undergoing Systemic Therapy

Source: ClinicalTrials.gov · Last updated 22 Oct 2026

Brief summary (registry, in English)

The skin microbiome plays a role in the pathogenesis of atopic dermatitis. However, it is unclear whether the range of microbiota on the skin is the cause or consequence of atopic skin inflammation. The influence of new systemic therapies for the treatment of moderate to severe atopic dermatitis (such as biologics or Janus kinase inhibitors) on the skin microbiome is largely unknown. The main aim of this scientific exploratory study is to investigate whether and how the skin microbiome changes in patients with moderate to severe atopic dermatitis during systemic therapy. This not only allows new hypotheses to be generated on the pathogenesis of atopic dermatitis, but also new objective scales for the severity of atopic dermatitis can be developed.

Status (registry)
Recruiting
Study type
Observational
Enrollment
600 (estimated)
First submitted
20 Jul 2021
Start date
Oct 2019
Primary completion date
Dec 2026
Lead sponsor
Charite University, Berlin, Germany
NCT number
NCT05099315

What you commit to

  • Study type: Observational
  • Planned participants: 600
  • From Oct 2019 to the primary completion date, Dec 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Age

  • Patients under 18 years of age upon introducing systemic therapy

Other

  • Pregnant and lactating women

Who the study is looking for

  • Patients with moderate to severe atopic dermatitis
  • Indication for systemic therapy

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Dpt of Dermatology and Allergology, Charité - Universitätsmedizin Berlin
Coordinator of this site? Confirm its status
BerlinGermanyRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.