NCT05099315Recruiting
Microbiome in Atopic Dermatitis Under Systemic Therapy
Identification of Skin-associated Microbiota in Atopic Dermatitis Patients Undergoing Systemic Therapy
Source: ClinicalTrials.gov · Last updated 22 Oct 2026
Brief summary (registry, in English)
The skin microbiome plays a role in the pathogenesis of atopic dermatitis. However, it is unclear whether the range of microbiota on the skin is the cause or consequence of atopic skin inflammation. The influence of new systemic therapies for the treatment of moderate to severe atopic dermatitis (such as biologics or Janus kinase inhibitors) on the skin microbiome is largely unknown. The main aim of this scientific exploratory study is to investigate whether and how the skin microbiome changes in patients with moderate to severe atopic dermatitis during systemic therapy. This not only allows new hypotheses to be generated on the pathogenesis of atopic dermatitis, but also new objective scales for the severity of atopic dermatitis can be developed.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 600 (estimated)
- First submitted
- 20 Jul 2021
- Start date
- Oct 2019
- Primary completion date
- Dec 2026
- Lead sponsor
- Charite University, Berlin, Germany
- Diseases
- Atopic dermatitis (eczema)
- NCT number
- NCT05099315
What you commit to
- Study type: Observational
- Planned participants: 600
- From Oct 2019 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Patients under 18 years of age upon introducing systemic therapy
Other
- Pregnant and lactating women
Who the study is looking for
- Patients with moderate to severe atopic dermatitis
- Indication for systemic therapy
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Dpt of Dermatology and Allergology, Charité - Universitätsmedizin Berlin Coordinator of this site? Confirm its status | Berlin | Germany | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.