NCT05108987Completed
Exercise and Time of Day in Type 2 Diabetes
Exercise Time of Day for Cardiometabolic Health in Type 2 Diabetes
Source: ClinicalTrials.gov · Last updated 18 May 2026
Brief summary (registry, in English)
The overall purpose of the study is to test the effect exercise time of day in adults with type 2 diabetes or prediabetes. The overarching hypothesis is that afternoon exercise in the afternoon may promote better changes in metabolic and vascular insulin sensitivity. We anticipate that these changes will correlate with glycemic control and blood pressure changes.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 36 (actual)
- First submitted
- 26 Oct 2021
- Start date
- 25 Sept 2021
- Primary completion date
- 17 Dec 2025
- Lead sponsor
- Rutgers, The State University of New Jersey
- Diseases
- Type 2 diabetes
- NCT number
- NCT05108987
What you commit to
- Study type: Interventional
- Participants enrolled: 36
- From 25 Sept 2021 to the primary completion date, 17 Dec 2025
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently taking active weight suppression medication (e.g. phentermine,orlistat, lorcaserin, naltrexone-bupropion in combination, liraglutide, benzphetamine, diethylpropion, phendimetrazine)
Other illness
- Evidence of type 1 diabetes and diabetics requiring insulin therapy.
- Subjects with a history of significant metabolic, cardiac, congestive heart failure, cerebrovascular, hematological, pulmonary, gastrointestinal, liver, renal, or endocrine disease or cancer that in the investigator's opinion would interfere with, alter the outcome measures, or impact subject safety.
- Known hypersensitivity to perflutren (contained in Definity)
Lab values
- Subjects with abnormal estimated glomerular filtration rate (eGFR).
- Hypertriglyceridemic (\>400 mg/dl) and hypercholesterolemic (\>260 mg/dl) subjects
Age
- Subjects who are smokers or who have quit smoking \<1 years ago
Other
- Morbidly obese patients (BMI \>45 kg/m2) and lean patients (BMI \<25 kg/m2)
- Subjects who have not been weight stable (\>2 kg weight change in past 3 months)
- Subjects who have been recently active (\>30 min of moderate/high intensity exercise, 3 times/week).
- Hypertensive (\>160/100 mmHg)
- Pregnant (as evidenced by positive urine pregnancy test) or nursing women.
- Subjects with contraindications to participation in an exercise training program
Who the study is looking for
- Male or female \>30 and \<80 years old.
- Has a body mass index \>25 and \<45 kg/m2.
- Previously diagnosed with prediabetes and/or T2D.
- If not previously diagnosed, has a fasting blood glucose ≥ 100 mg/dL and/or HbA1c ≥ 5.7%
Age in the registry: 30 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Rutgers University Loree Gymnasium Coordinator of this site? Confirm its status | New Brunswick | United States | Unknown status |
| New Jersey Institute for Food, Nutrition, and Health Coordinator of this site? Confirm its status | New Brunswick | United States | Unknown status |
| Robert Wood Johnson University Hospital Clinical Research Center Coordinator of this site? Confirm its status | New Brunswick | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.