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NCT05113043Recruiting

Correlation Between Intestinal Microecology Imbalance and Stroke in Young Adults

Research on Correlation Between Intestinal Microecology Imbalance and the Risk and Prognosis of Stroke in Young Adults

Source: ClinicalTrials.gov · Last updated 23 Apr 2026

Brief summary (registry, in English)

The relationship between the intestinal microecology and stroke has become a research hotspot in neurology field today. Maintaining the balance of the intestinal microbiota are expected to bring new breakthroughs for prevention and treatment of stroke. In recent years, stroke in young adults has an increasing incidence and a considerable socioeconomic impact because of high disability rate and health-care costs. So there is an urgent need to explore the role and mechanism of intestinal microecology imbalance in stroke, especially in the development and prognosis of stroke in young people. This study aims to use multi-omics technologies, including microbial diversity, metagenomics and metabonomics, to reveal the characteristics of intestinal flora in young stroke patients, identify biomarkers for predicting outcome after stroke and early detection of young people at high risk of stroke, and to further explore the role of gut-brain axis in the pathogenesis of stroke.

Status (registry)
Recruiting
Study type
Observational
Enrollment
60 (estimated)
First submitted
5 Nov 2021
Start date
1 Feb 2022
Primary completion date
31 Dec 2027
Lead sponsor
Shanghai 6th People's Hospital
Diseases
Stroke
NCT number
NCT05113043

What you commit to

  • Study type: Observational
  • Planned participants: 60
  • From 1 Feb 2022 to the primary completion date, 31 Dec 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • History of neurological diseases, myocardial infarction, renal and hepatic abnormalities and metabolic diseases
  • Combined with tumors, inflammatory bowel disease and other digestive system diseases
  • Combined with serious life-threatening diseases or condition

Other

  • Any antibiotics, probiotics or prebiotic treatment within 3 months
  • Deteriorate and die before collecting faecal samples

Who the study is looking for

  • Clinical diagnosis of acute ischemic or hemorrhagic stroke
  • Admission within 12 hours
  • Aged 18-45 years

Age in the registry: 18 years to 45 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Shanghai 6th People's Hospital
Coordinator of this site? Confirm its status
ShanghaiChinaNot yet recruiting

This page is information, not medical advice. Discuss any trial with your doctor.