NCT05116943Recruiting
Biospecimen Biorepository for the Study of ALS, ALS-FTD and Similar Neurodegenerative Disorders
Source: ClinicalTrials.gov · Last updated 16 Dec 2025
Brief summary (registry, in English)
The purpose of this study is to collect CSF and blood samples that can be used in future research studies to identify potential biomarkers in blood and cerebrospinal fluid (CSF) collected in Amyotrophic Lateral Sclerosis (ALS) patients.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 100 (estimated)
- First submitted
- 2 Nov 2021
- Start date
- 19 Aug 2013
- Primary completion date
- Jan 2030
- Lead sponsor
- Mayo Clinic
- Diseases
- ALS (motor neurone disease)
- NCT number
- NCT05116943
What you commit to
- Study type: Observational
- Planned participants: 100
- From 19 Aug 2013 to the primary completion date, Jan 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of medical disorder that leaves in question whether neurological signs and symptoms potentially related to a neurodegenerative disease may be caused by another unrelated disorder.
- For lumbar puncture, an increased risk of bleeding complications or allergy to local anesthetic administered or skin antiseptic used for lumbar puncture.
- For lumbar puncture, an increased risk of bleeding complications or allergy to local anesthetic administered or skin antiseptic used for lumbar puncture.
Other
- Limited mental capacity rendering the subject unable to comply with lumbar puncture or standard phlebotomy procedures.
- Limited mental capacity rendering the subject unable to comply with lumbar puncture or standard phlebotomy procedures.
Who the study is looking for
- Clinical diagnosis of possible, laboratory-supported probable, probable or definite ALS according to modified eL Escorial criteria, suspected ALS according to original el Escorial criteria, or diagnosis of a similar neurodegenerative disorder.
- Willing to provide consent, or assent, if physically unable to consent owing to disease-related muscle weakness.
- No personal history of ALS, ALS-FTD or other motor neuron disease.
- Subjects with family history of ALS, ALS-FTD the affected family member needs to be a first, second, or third degree blood relative.
- Willing to provide consent.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Clinic in Florida Coordinator of this site? Confirm its status | Jacksonville | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.