NCT05118308Completed
EUS vs TJ for Liver Biopsy and Portal Pressure Gradient Measurement
Endoscopic Ultrasound Guided Liver Biopsy and Portal Pressure Gradient Measurement Compared to the Transjugular Approach: a Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 17 Apr 2026
Brief summary (registry, in English)
This study will directly compare the endoscopic ultrasound guided approach to obtain adequate liver biopsies and portal pressure gradient measurements to the current standard of care which uses the transjugular approach.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 58 (actual)
- First submitted
- 22 Oct 2021
- Start date
- 4 Nov 2021
- Primary completion date
- 1 Dec 2024
- Lead sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
- Diseases
- High blood pressure
- NCT number
- NCT05118308
What you commit to
- Study type: Interventional
- Participants enrolled: 58
- From 4 Nov 2021 to the primary completion date, 1 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Anticoagulation or antiplatelet therapy that cannot be discontinued
- Previous liver transplantation
Other illness
- Intrahepatic portal vein thrombosis
- Past hypersensitivity reaction to midazolam or ketamine
- History of psychotic disorder
Lab values
- Uncorrectable coagulopathy (INR above 1.5)
- Uncorrectable thrombocytopenia (Platelets under 50,000)
Other
- Surgically altered upper digestive anatomy
- Biliary obstruction
- Grade II ascites or more
- Pregnancy
Who the study is looking for
- Age above 18 years
- Undergoing evaluation for chronic liver disease or portal hypertension
- Planned to undergo a liver biopsy and HVPG by their treating hepatologist for clinical purposes
- Signed informed consent
Age in the registry: 18 years to 100 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| McGill University Health Centre Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.