NCT05121519Completed
Does Eliminating Coffee Avoid Fibrillation?
A Randomized Controlled Trial to Assess Abstinence of Coffee Compared to Continued Consumption on Recurrent Atrial Fibrillation Following Cardioversion
Source: ClinicalTrials.gov · Last updated 26 Nov 2025
Brief summary (registry, in English)
Given both the increasing population impact of atrial fibrillation (AF) and the widespread consumption of coffee in society, determining an associated benefit or risk of coffee consumption on AF is of great clinical relevance. This study will evaluate the effect of randomly assigning participants undergoing cardioversion to coffee abstinence or coffee continuation over a 6 month period. This study will provide the first, randomized evaluation of coffee on AF outcomes and will provide important information on whether or not coffee has any effect on AF recurrence.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 200 (actual)
- First submitted
- 26 Oct 2021
- Start date
- 20 Oct 2021
- Primary completion date
- 5 Jun 2025
- Lead sponsor
- University of California, San Francisco
- Diseases
- Atrial fibrillation
- NCT number
- NCT05121519
What you commit to
- Study type: Interventional
- Participants enrolled: 200
- From 20 Oct 2021 to the primary completion date, 5 Jun 2025
- 3 sites in 3 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recent cardiothoracic surgery in preceding 3 months
- Current enrollment in an investigation or study of a cardiovascular device or investigational drug that would interfere with this study
- Any other criteria, which would make the patient unsuitable to participate in this study as determined by the Principal Investigator (e.g., an uncontrolled drug and/or alcohol addiction)
Other illness
- Established allergy or adverse reaction to coffee
Other
- Stated inability to comply with coffee abstinence or continuation
- AF ablation in preceding 3 months or planned in next 3 months
- Pregnancy or desire to get pregnant within next 6 months.
Who the study is looking for
- Men or women ≥ 21 years of age
- Sustained AF or atrial flutter (provided patient has a history of AF)
- Planned/scheduled direct current electrical cardioversion
- Consumption greater than or equal to one cup of coffee per day sometime in the past 5 years
- Willing and able to comply with coffee abstinence or continuation for at least 6 months
- Life expectancy of at least 6 months
- Willing and able to return and comply with scheduled phone follow up visits
- Willing and able to provide written informed consent
Age in the registry: 21 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Royal Adelaide Hospital Coordinator of this site? Confirm its status | Adelaide | Australia | Unknown status |
| Sunnybrook Health Science Centre Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
| UCSF Parnassus Coordinator of this site? Confirm its status | San Francisco | United States | Unknown status |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.