NCT05131035Recruiting
Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk
Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk in Adolescents at Clinical High Risk for Psychosis
Source: ClinicalTrials.gov · Last updated 24 Nov 2025
Brief summary (registry, in English)
This 10 week intervention, Specific Cognitive Remediation with Surround (or SCORES), is designed to target processing speed, a cognitive domain related directly to social functioning, which in turn, represents a vulnerability factor for psychosis. This remotely-delivered intervention combining targeted cognitive training exercises and group support was developed to directly impact processing speed, and at the same time, boost motivation and engagement in adolescents at risk for schizophrenia and other psychotic disorders.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 54 (estimated)
- First submitted
- 11 Nov 2021
- Start date
- 28 Oct 2021
- Primary completion date
- 31 May 2026
- Lead sponsor
- Northwell Health
- Diseases
- Schizophrenia
- NCT number
- NCT05131035
What you commit to
- Study type: Interventional
- Planned participants: 54
- From 28 Oct 2021 to the primary completion date, 31 May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Past or current history of a clinically significant central nervous system disorder (e.g., seizure disorder)
- Significant visual or auditory impairment.
Other
- Any DSM 5 Schizophrenia-Spectrum diagnosis
- Non-English speaking
- Estimated IQ\<70
- Significant head injury
- Significant substance abuse
Who the study is looking for
- Meet Clinical High Risk (CHR) criteria on the Structured Interview for Psychosis Risk Syndromes, defined by the presence of at least one attenuated positive symptom at a moderate to severe level
- A score representing 0.5 SD below the mean on Animal Naming, Trails A or BACS: Symbol Coding from the MATRICS Consensus Cognitive Battery (MCCB).
Age in the registry: 14 years to 20 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Northwell Health- The Zucker Hillside Hospital Coordinator of this site? Confirm its status | Glen Oaks | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.