NCT05135533Completed
Neuromodulation and Dynamic Balance in Stroke
Cranial-nerve Non-invasive Neuromodulation and Dynamic Balance in Chronic Stroke Survivors
Source: ClinicalTrials.gov · Last updated 13 Aug 2026
Brief summary (registry, in English)
Portable Neuromodulation Stimulator (PoNS) is non-invasive stimulation device placed on the tongue to stimulate those brain regions understood to be important for maintaining balance. This research study aims to collect evidence that PoNS therapy along with balance training improves postural and walking stability post-stroke.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 53 (actual)
- First submitted
- 15 Nov 2021
- Start date
- 28 Aug 2023
- Primary completion date
- 24 Jul 2025
- Lead sponsor
- Medical University of South Carolina
- Diseases
- Stroke
- NCT number
- NCT05135533
What you commit to
- Study type: Interventional
- Participants enrolled: 53
- From 28 Aug 2023 to the primary completion date, 24 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous stroke affecting the other hemisphere .
- Received treatment for cancer within the past year.
Other illness
- Pre-existing neurological disorders.
- Areas of recent bleeding or open wounds.
- Chronic infectious diseases.
- Have dementia
Other
- Severe arthritis or orthopedic problems that limit passive range of motion.
- Lack normal sensation on the tongue.
- Non-removable metal orthodontic devices.
- Oral health problems.
- Are sensitive to nickel, gold or copper.
- Are pregnant.
Who the study is looking for
- At least six months since the onset of Ischemic or hemorrhagic stroke.
- Demonstrate residual paresis in the lower extremity (Fugl-Mayer lower extremity score \< 34).
- Are able to provide informed consent demonstrated by their ability to weigh the consequences of participating versus not participating in the study.
- Can walk at least 10 feet with and without assistive device.
- Functional Gait Assessment score \<22.
Age in the registry: 22 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical University of South Carolina Coordinator of this site? Confirm its status | Charleston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.