NCT05136222Recruiting
Polysomnographic Titration of Non-invasive Ventilation in Motor Neurone Disease
A Multi-centre Randomised Controlled Trial of Polysomnographic Titration of Non-invasive Ventilation in Motor Neurone Disease (PSG4NIVinMND; 3, Three Letter Acronyms [3TLA])
Source: ClinicalTrials.gov · Last updated 23 Jun 2022 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
A two-arm, individual participant randomised controlled, assessor-blinded trial in 7 MND care centres across Australia will be undertaken.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 244 (estimated)
- First submitted
- 21 Oct 2021
- Start date
- 15 Dec 2021
- Primary completion date
- 28 Feb 2026
- Lead sponsor
- University of Melbourne
- Diseases
- ALS (motor neurone disease)
- NCT number
- NCT05136222
What you commit to
- Study type: Interventional
- Planned participants: 244
- From 15 Dec 2021 to the primary completion date, 28 Feb 2026
- 13 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Hypoventilation attributable to medications with sedative/respiratory depressant side- effects
- Use of NIV for more than 1 month in the previous 3 months
- Previous intolerance of NIV
Other
- Medically unstable
- Inability to provide informed consent
Who the study is looking for
- Age \>18 years
- Clinical indication to commence long term NIV
- Confirmed clinical diagnosis of underlying condition
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (13)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Flinders Medical Centre Coordinator of this site? Confirm its status | Adelaide | Australia | Not yet recruiting |
| The Prince Charles Hospital Coordinator of this site? Confirm its status | Brisbane | Australia | Not yet recruiting |
| Motor Neurone Disease Australia Coordinator of this site? Confirm its status | Canberra | Australia | Not yet recruiting |
| Australian MND Registry Coordinator of this site? Confirm its status | Melbourne | Australia | Not yet recruiting |
| Institute for Breathing and Sleep Coordinator of this site? Confirm its status | Melbourne | Australia | Not yet recruiting |
| Austin Health Coordinator of this site? Confirm its status | Melbourne | Australia | Recruiting |
| Monash University Coordinator of this site? Confirm its status | Melbourne | Australia | Not yet recruiting |
| FightMND Coordinator of this site? Confirm its status | Melbourne | Australia | Not yet recruiting |
| University of Melbourne Coordinator of this site? Confirm its status | Melbourne | Australia | Not yet recruiting |
| Sir Charles Gairdner Hospital Coordinator of this site? Confirm its status | Perth | Australia | Not yet recruiting |
| Royal Prince Alfred Hospital Coordinator of this site? Confirm its status | Sydney | Australia | Not yet recruiting |
| Westmead Hospital Coordinator of this site? Confirm its status | Sydney | Australia | Not yet recruiting |
| Macquarie University Coordinator of this site? Confirm its status | Sydney | Australia | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.