NCT05139420Active, not recruiting
Risk of Metabolic Adaptation After Weight Loss
Biomarkers of Increased Risk of Developing Metabolic Adaptation to Weight Loss
Source: ClinicalTrials.gov · Last updated 11 Feb 2026
Brief summary (registry, in English)
This study aims at identifying the neurohormonal biomarkers that characterize individuals at risk of greater metabolic adaptation to weight loss, a disproportionate decline in resting metabolic rate during and after weight loss.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 18 Nov 2021
- Start date
- 10 Sept 2022
- Primary completion date
- Nov 2031
- Lead sponsor
- Medical College of Wisconsin
- Diseases
- Obesity
- NCT number
- NCT05139420
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 10 Sept 2022 to the primary completion date, Nov 2031
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- post solid organ or bone marrow transplant
- current recreational drug use
Other illness
- diabetes (type 2 or type 1)
- hypertension
- heart disease
- kidney disease
- liver disease
- active cancer
- HIV/AIDS
Other
- weight \> or = 400 lbs.
- pregnancy
- breastfeeding
- current smoker
Who the study is looking for
- BMI \> or = 30 any ethnicity
Age in the registry: 18 years to 50 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical College of Wisconsin Coordinator of this site? Confirm its status | Milwaukee | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.