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NCT05139797Recruiting

Artificial Intelligence Guided Echocardiographic Screening of Rare Diseases (EchoNet-Screening)

Artificial Intelligence Guided Echocardiographic Screening of Rare Diseases

Source: ClinicalTrials.gov · Last updated 22 Jul 2026

Brief summary (registry, in English)

Despite rapidly advancing developments in targeted therapeutics and genetic sequencing, persistent limits in the accuracy and throughput of clinical phenotyping has led to a widening gap between the potential and the actual benefits realized by precision medicine. Recent advances in machine learning and image processing techniques have shown that machine learning models can identify features unrecognized by human experts and more precisely/accurately assess common measurements made in clinical practice. The investigators have developed an algorithm, termed EchoNet-LVH, to identify cardiac hypertrophy and identify patients who would benefit from additional screening for cardiac amyloidosis and will prospectively evaluate its accuracy in identifying patients whom would benefit from additional screening for cardiac amyloidosis.

Status (registry)
Recruiting
Study type
Observational
Enrollment
300 (estimated)
First submitted
18 Nov 2021
Start date
18 Nov 2021
Primary completion date
1 Jan 2027
Lead sponsor
Cedars-Sinai Medical Center
Diseases
Amyloidosis
NCT number
NCT05139797

What you commit to

  • Study type: Observational
  • Planned participants: 300
  • From 18 Nov 2021 to the primary completion date, 1 Jan 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Patients who decline to be seen at specialty clinic
  • Patients who have passed away

Who the study is looking for

  • Patients who have a high suspicion for cardiac amyloidosis by AI algorithm

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Cedars-Sinai Medical Centre (Los Angeles)
Coordinator of this site? Confirm its status
Los AngelesUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.