NCT05139992Completed
COVID-19 Vaccine Response in Sickle Cell Disease
COVID-19 Vaccine Response in People Living With Sickle Cell Disease
Source: ClinicalTrials.gov · Last updated 14 Feb 2025
Brief summary (registry, in English)
The purpose of this study is to assess the antibody response to COVID-19 vaccination in a cohort of patients with sickle cell disease (SCD) and to assess vaccine and SCD related complications around the time of vaccination.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 59 (actual)
- First submitted
- 29 Nov 2021
- Start date
- 1 Dec 2021
- Primary completion date
- 31 Dec 2023
- Lead sponsor
- ASH Research Collaborative
- Diseases
- Sickle cell disease
- NCT number
- NCT05139992
What you commit to
- Study type: Observational
- Participants enrolled: 59
- From 1 Dec 2021 to the primary completion date, 31 Dec 2023
- 8 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous therapy curative of SCD (including bone marrow transplant and gene therapy)
- Previous receipt of anti-COVID-19 antibody therapy
Other
- Unwilling to have labs drawn or complete study requirements.
Who the study is looking for
- Diagnosis of sickle cell disease (HbSS, HbSC, HbSB0 thalassemia, HbSB+ thalassemia, HbS/Other)
- Has not received any COVID-19 vaccination prior to enrollment
- Scheduled for a COVID-19 vaccination (type does not matter) as part of routine clinical care
- Willing and able to sign consent
Sex: All · Does not accept healthy volunteers
Sites (8)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Johns Hopkins University Coordinator of this site? Confirm its status | Baltimore | United States | Unknown status |
| University of Texas Southwestern Medical Center Coordinator of this site? Confirm its status | Dallas | United States | Unknown status |
| Duke University Medical Center Coordinator of this site? Confirm its status | Durham | United States | Unknown status |
| Prisma Health-Upstate Coordinator of this site? Confirm its status | Greenville | United States | Unknown status |
| Medical College of Wisconsin Coordinator of this site? Confirm its status | Milwaukee | United States | Unknown status |
| UCSF Benioff Children's Hospital Oakland Coordinator of this site? Confirm its status | Oakland | United States | Unknown status |
| Montefiore Hospital Coordinator of this site? Confirm its status | The Bronx | United States | Unknown status |
| Children's National Medical Center Coordinator of this site? Confirm its status | Washington D.C. | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.