NCT05140226Completed
Cognitive and Physical Training in Patients With Chronic Obstructive Pulmonary Disease Patients
Feasibility of a Home-Based Cognitive-Physical Exercise Program in Chronic Obstructive Pulmonary Disease (COPD) Patients: A Pilot Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 29 Sept 2025
Brief summary (registry, in English)
Cognitive and physical function impairments are common in patients diagnosed with Chronic Obstructive Pulmonary Disease (COPD). Research has shown that cognitive and physical exercise training may be a beneficial strategy to improve physical and cognitive performance in COPD patients; however, interventions combining physical and cognitive training have not been evaluated in this population. The objectives of this research are i) to evaluate the feasibility of an 8-week home-based cognitive-physical training program in COPD patients; and ii) to derive preliminary estimates on intervention efficacy with cognitive-physical training on dual-task performance, physical function, activities of daily living, and health-related quality of life. Related to our research objectives, we hypothesize that i) it will be feasible to safely recruit COPD patients into a home-based cognitive physical training program with 75% adherence and high satisfaction ratings with the prescribed training; and that ii) the combination of cognitive and physical training will be superior to physical training alone for improving dual-task and cognitive performance, physical function, activities of daily living, and health-related quality of life.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 24 (actual)
- First submitted
- 17 Nov 2021
- Start date
- 1 Mar 2022
- Primary completion date
- 22 Sept 2025
- Lead sponsor
- University Health Network, Toronto
- Diseases
- COPD
- NCT number
- NCT05140226
What you commit to
- Study type: Interventional
- Participants enrolled: 24
- From 1 Mar 2022 to the primary completion date, 22 Sept 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patient on home oxygen therapy
- Patient actively listed for lung transplantation
Other illness
- Disease exacerbation in the past 3 months
- Diagnosis of a neurological or musculoskeletal condition that would interfere with safe performance of study tests (e.g., stroke, myopathy, inflammatory arthritis)
- Severe cognitive impairment ascertained by chart review or self-reported
- Coronary artery disease, pacemaker or implantable defibrillator, clinical diagnosis of congestive heart failure (CHF), or poorly controlled arrhythmias
- Medical instability (hepatic dysfunction, metabolic abnormalities, or active infection)
- Overt psychiatric disorder or substance abuse
Other
- Current participation in a pulmonary rehabilitation program
- Insufficient English fluency and cognition to carry out testing and training
Who the study is looking for
- Adult participants (≥ 50 years of age)
- Clinical and spirometric diagnosis of COPD (FEV1 30-80%)
- Access to reliable internet connection
- Ability to mobilize independently and safely, with or without a walking aid
Age in the registry: 50 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Health Network Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.