NCT05143021Active, not recruiting
Sickle Cell Disease Obstetric Multi-Disciplinary Care Programme
Sickle Cell Disease Obstetric Multi-Disciplinary Care Programme: Prospective Multi-Centre Cohort Study
Source: ClinicalTrials.gov · Last updated 13 Apr 2026
Brief summary (registry, in English)
To implement an effective but low-cost strategy to decrease SCD maternal and perinatal mortality in Ghana. The objectives are to 1) assess the impact of a multidisciplinary SCD-obstetric team for decreasing mortality across three hospital sites in Ghana. 2) assess the implementation fidelity for 2a) preventing and 2b) treating acute chest syndrome in pregnant women with SCD admitted to the hospital. 3) standardize an ultrasound protocol for the prospective monitoring of fetal growth among pregnant women with SCD.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 500 (estimated)
- First submitted
- 19 Nov 2021
- Start date
- 14 Feb 2022
- Primary completion date
- 28 Feb 2026
- Lead sponsor
- Vanderbilt University Medical Center
- Diseases
- Sickle cell disease
- NCT number
- NCT05143021
What you commit to
- Study type: Observational
- Planned participants: 500
- From 14 Feb 2022 to the primary completion date, 28 Feb 2026
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- All pregnant women without a confirmed Hb phenotype or electrophoresis report
- All pregnant women with SCD who present to the Greater Accra Regional Hospital or Tamale Teaching Hospital for acute admissions, labor, and delivery
- All pregnant women with SCD with undetermined Hb phenotypes on Hb electrophoresis.
Who the study is looking for
- All study participants will be adults between the reproductive ages of 18 to 45 years as defined by World Health Organization (WHO)
- Confirmed SCD status by Hb-electrophoresis in alkaline medium
- Pregnancy should be confirmed by urine or blood pregnancy test and pelvic ultrasound scan.
Age in the registry: 18 years to 45 years · Sex: Female · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Greater Accra Regional Hospital Coordinator of this site? Confirm its status | Accra | Ghana | Unknown status |
| Korle Bu Teaching Hospital Coordinator of this site? Confirm its status | Accra | Ghana | Unknown status |
| Tamale Teaching Hospital Coordinator of this site? Confirm its status | Tamale | Ghana | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.